PIPA597391
Phospho-MYPT1 (Ser507) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA597391-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA597391 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Phospho-MYPT1 (Ser507)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PPP1R12A
Gene Alias
1200015F06Rik, 130 kDa myosin-binding subunit of smooth muscle myosin phophatase, 130 kDa myosin-binding subunit of smooth muscle myosin phophatase (M130), 130 kDa myosin-binding subunit of smooth muscle myosin phosphatase, 130 kDa regulatory subunit of myosin phosphatase, 133kDa myosin-binding subunit of smooth muscle myosin phosphatase (M133), 5730577I22Rik, AA792106, AV099298, D10Ertd625e, hypothetical protein, I79_016312, LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 12A, M110, M130, M130 of smooth muscle myosin phosphatase, MBS, MBSP, myosin binding subunit, myosin phosphatase target subunit 1, myosin phosphatase, target subunit 1, myosin phosphatase-targeting subunit 1, myosin-binding subunit of myosin phosphatase, Mypt1, PP-1M, PP1M M110 subunit, PP1M subunit M110, Ppp1r12a, Protein phosphatase 1 regulatory subunit 12A, protein phosphatase 1, regulatory (inhibitor) subunit 12A, protein phosphatase 1, regulatory subunit 12A, protein phosphatase 1M 110 kda regulato
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4659
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.24 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
O14974
Gene Symbols
PPP1R12A
Immunogen
A synthetic phosphorylated peptide around S507 of human PPP1R12A (NP_0011373571)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: LASTS; Positive Samples: HeLa, Jurkat; Cellular Location: Cytoplasm Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase
- Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho
- The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells
- The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP
- RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC
- Rho-associated kinase (Rho-kinase), which is activated by GTP
- RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase
- Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC
- Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase
- Several transcript variants encoding different isoforms have been found for this gene.
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Antigen: Phospho-MYPT1 (Ser507)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PPP1R12A
Gene Alias: 1200015F06Rik, 130 kDa myosin-binding subunit of smooth muscle myosin phophatase, 130 kDa myosin-binding subunit of smooth muscle myosin phophatase (M130), 130 kDa myosin-binding subunit of smooth muscle myosin phosphatase, 130 kDa regulatory subunit of myosin phosphatase, 133kDa myosin-binding subunit of smooth muscle myosin phosphatase (M133), 5730577I22Rik, AA792106, AV099298, D10Ertd625e, hypothetical protein, I79_016312, LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 12A, M110, M130, M130 of smooth muscle myosin phosphatase, MBS, MBSP, myosin binding subunit, myosin phosphatase target subunit 1, myosin phosphatase, target subunit 1, myosin phosphatase-targeting subunit 1, myosin-binding subunit of myosin phosphatase, Mypt1, PP-1M, PP1M M110 subunit, PP1M subunit M110, Ppp1r12a, Protein phosphatase 1 regulatory subunit 12A, protein phosphatase 1, regulatory (inhibitor) subunit 12A, protein phosphatase 1, regulatory subunit 12A, protein phosphatase 1M 110 kda regulato
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4659
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.24 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: O14974
Gene Symbols: PPP1R12A
Immunogen: A synthetic phosphorylated peptide around S507 of human PPP1R12A (NP_0011373571)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-MYPT1 (Ser507)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PPP1R12A
Gene Alias:
1200015F06Rik, 130 kDa myosin-binding subunit of smooth muscle myosin phophatase, 130 kDa myosin-binding subunit of smooth muscle myosin phophatase (M130), 130 kDa myosin-binding subunit of smooth muscle myosin phosphatase, 130 kDa regulatory subunit of myosin phosphatase, 133kDa myosin-binding subunit of smooth muscle myosin phosphatase (M133), 5730577I22Rik, AA792106, AV099298, D10Ertd625e, hypothetical protein, I79_016312, LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 12A, M110, M130, M130 of smooth muscle myosin phosphatase, MBS, MBSP, myosin binding subunit, myosin phosphatase target subunit 1, myosin phosphatase, target subunit 1, myosin phosphatase-targeting subunit 1, myosin-binding subunit of myosin phosphatase, Mypt1, PP-1M, PP1M M110 subunit, PP1M subunit M110, Ppp1r12a, Protein phosphatase 1 regulatory subunit 12A, protein phosphatase 1, regulatory (inhibitor) subunit 12A, protein phosphatase 1, regulatory subunit 12A, protein phosphatase 1M 110 kda regulato
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4659
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.24 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
O14974
Gene Symbols:
PPP1R12A
Immunogen:
A synthetic phosphorylated peptide around S507 of human PPP1R12A (NP_0011373571)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-JAK2 (Tyr1008)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: JAK2
Gene Alias: EC 2.7.10.2, Fd17, JAK 2, JAK2, JAK-2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK 10, JTK10, kinase Jak2, THCYT3, Tyrosine-protein kinase JAK2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3717
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.66 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: O60674
Gene Symbols: JAK2
Immunogen: A synthetic phosphorylated peptide around Y1008 of human Phospho-JAK2-Y1008 (NP_0049631)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-JAK2 (Tyr1008)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
JAK2
Gene Alias:
EC 2.7.10.2, Fd17, JAK 2, JAK2, JAK-2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK 10, JTK10, kinase Jak2, THCYT3, Tyrosine-protein kinase JAK2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3717
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.66 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
O60674
Gene Symbols:
JAK2
Immunogen:
A synthetic phosphorylated peptide around Y1008 of human Phospho-JAK2-Y1008 (NP_0049631)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-eIF4B (Ser422)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Eif4b
Gene Alias: 2310046H11Rik, AL024095, C85189, Eif4a2, EIF4B, eIF-4B, Eukaryotic translation initiation factor 4B, hCG_2014609, hypothetical protein, PRO1843
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1975
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P23588
Gene Symbols: Eif4b
Immunogen: A synthetic phosphorylated peptide around S422 of human EIF4B (NP_0014082)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-eIF4B (Ser422)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Eif4b
Gene Alias:
2310046H11Rik, AL024095, C85189, Eif4a2, EIF4B, eIF-4B, Eukaryotic translation initiation factor 4B, hCG_2014609, hypothetical protein, PRO1843
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1975
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P23588
Gene Symbols:
Eif4b
Immunogen:
A synthetic phosphorylated peptide around S422 of human EIF4B (NP_0014082)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Lamin A/C (Ser22)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LMNA
Gene Alias: 70 kDa lamin, cb948, CDCD1, CDDC, CMD1A, CMT2B1, Dhe, EMD2, FPL, FPLD, FPLD2, HGPS, I79_009616, IDC, lamin, lamin A, lamin A/C, lamin A/C L homeolog, lamin A/C-like 1, Lamin A+C mutant, Lamin AC, lamin a-c, lamin C, lamin C2, lamin-A, Lamin-A/C, LDP1, LFP, LGMD1B, LMN1, lmna, LMNA protein, lmna.L, lmna-A, LMNC, LMNL1, mutant 453W, Mutant lamin A/C, nuclear intermediate filament protein, nuclear lamin A, prelamin-A/C, PRO1, progerin mutant, Renal carcinoma antigen NY-REN-32, RP11-54H19.1, unnamed protein product, wu:fk66d12, XELAEV_18040808mg
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4000, 60374
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 0.43 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P02545, P48679
Gene Symbols: LMNA
Immunogen: A synthetic phosphorylated peptide around S22 of human Lamin A (NP_0055631)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Lamin A/C (Ser22)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LMNA
Gene Alias:
70 kDa lamin, cb948, CDCD1, CDDC, CMD1A, CMT2B1, Dhe, EMD2, FPL, FPLD, FPLD2, HGPS, I79_009616, IDC, lamin, lamin A, lamin A/C, lamin A/C L homeolog, lamin A/C-like 1, Lamin A+C mutant, Lamin AC, lamin a-c, lamin C, lamin C2, lamin-A, Lamin-A/C, LDP1, LFP, LGMD1B, LMN1, lmna, LMNA protein, lmna.L, lmna-A, LMNC, LMNL1, mutant 453W, Mutant lamin A/C, nuclear intermediate filament protein, nuclear lamin A, prelamin-A/C, PRO1, progerin mutant, Renal carcinoma antigen NY-REN-32, RP11-54H19.1, unnamed protein product, wu:fk66d12, XELAEV_18040808mg
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4000, 60374
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
0.43 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P02545, P48679
Gene Symbols:
LMNA
Immunogen:
A synthetic phosphorylated peptide around S22 of human Lamin A (NP_0055631)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG