K4013

Kasugamycin hydrochloride from Streptomyces kasugaensis

Manufacturer: Sigma Aldrich

CAS Number: 19408-46-9

Synonym(S): 3-O-[2-Amino-4-[(carboxyiminomethyl)amino]-2,3,4,6-tetradeoxy-D-arabino-hexopyranosyl]-D-chiro-inositol

Select a Size

Pack Size SKU Availability Price
10 G K4013-10-G In Stock ₹ 29,909.48

K4013 - 10 G

₹ 29,909.48

In Stock

Quantity

1

Base Price: ₹ 29,909.48

GST (18%): ₹ 5,383.706

Total Price: ₹ 35,293.186

biological source

Streptomyces kasugaensis

Quality Level

200

form

powder

color

white to off-white

antibiotic activity spectrum

Gram-negative bacteriaGram-positive bacteria

Mode of action

protein synthesis | interferes

storage temp.

2-8°C

SMILES string

C[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H]2O)[C@@H](N)C[C@@H]1NC(C(O)=O)=N.Cl

InChI

1S/C14H25N3O9.ClH/c1-3-5(17-12(16)13(23)24)2-4(15)14(25-3)26-11-9(21)7(19)6(18)8(20)10(11)22;/h3-11,14,18-22H,2,15H2,1H3,(H2,16,17)(H,23,24);1H/t3-,4+,5+,6-,7+,8+,9-,10+,11+,14-;/m1./s1

InChI key

ZDRBJJNXJOSCLR-NZXABURVSA-N

Other Options

Image Product Name Manufacturer Price Range
32354
Kasugamycin hydrochloride
Supelco ₹ 6,159.43

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Description

  • General description: Chemical structure: aminoglycoside
  • Application: Kasugamycin (Ksg) is an aminoglycoside antibiotic isolated from Streptomyces kasugaensis. It is used to study ribosome structure and interactions near the m26A m26A sequence[1]. It is used to study the mechanisms of kasugamycin resistance[2].
  • Biochem/physiol Actions: Kasugamycin binds within the mRNA channel of the 30S subunit between the universally conserved G926 and A794 nucleotides in 16S ribosomal RNA[2]. It inhibits protein synthesis and binding of aminoacyl-sRNA to the ribosomes in fungi and induces f-met-tRNA dissociation from the P-site of the 30S subunit.

SAFETY INFORMATION

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Show Difference

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Sigma Aldrich

K4013

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biological source:
Streptomyces kasugaensis

Quality Level:
200

form:
powder

color:
white to off-white

antibiotic activity spectrum:
Gram-negative bacteriaGram-positive bacteria

Mode of action:
protein synthesis | interferes

storage temp.:
2-8°C

SMILES string:
C[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H]2O)[C@@H](N)C[C@@H]1NC(C(O)=O)=N.Cl

InChI:
1S/C14H25N3O9.ClH/c1-3-5(17-12(16)13(23)24)2-4(15)14(25-3)26-11-9(21)7(19)6(18)8(20)10(11)22;/h3-11,14,18-22H,2,15H2,1H3,(H2,16,17)(H,23,24);1H/t3-,4+,5+,6-,7+,8+,9-,10+,11+,14-;/m1./s1

InChI key:
ZDRBJJNXJOSCLR-NZXABURVSA-N

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[K+].OCC(=O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O

InChI:
1S/C6H10O7.K/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h3-5,7,9-11H,1H2,(H,12,13);/q;+1/p-1/t3-,4+,5-;/m1./s1

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