O8757
Ofloxacin
fluoroquinolone antibiotic
Manufacturer: Sigma Aldrich
CAS Number: 82419-36-1
Synonym(S): Dextrofloxacin
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 G | O8757-1-G | In Stock | ₹ 7,794.00 |
| 10 G | O8757-10-G | In Stock | ₹ 20,545.85 |
O8757 - 1 G
In Stock
Quantity
1
Base Price: ₹ 7,794.00
GST (18%): ₹ 1,402.92
Total Price: ₹ 9,196.92
biological source
synthetic
Quality Level
200
Assay
≥99% (HPLC)
form
powder
solubility
1 M NaOH: soluble 50 mg/mL
antibiotic activity spectrum
Gram-negative bacteriaGram-positive bacteriamycobacteria
Mode of action
DNA synthesis | interferesenzyme | inhibits
storage temp.
2-8°C
InChI
1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)
InChI key
GSDSWSVVBLHKDQ-UHFFFAOYSA-N
Other Options
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Description
- General description: Chemical structure: fluoroquinolone
- Application: Ofloxacin is a synthetic fluoroquinolone with broad-spectrum antibacterial activity. It is a nalidixic acid analog. It is given to patients before undergoing retinal reattachment surgery[1].
- Biochem/physiol Actions: Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, which haults DNA replication and cell division. Ofloxacin has been shown to convert LytA from the inactive E-form to the active C-form[2]. It is a chiral molecule that inhibits pneumococcal cell wall-degrading virulence factors[2].
- Other Notes: Keep container tightly closed in a dry and well-ventilated place.
SAFETY INFORMATION
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
biological source: synthetic
Quality Level: 200
Assay: ≥99% (HPLC)
form: powder
solubility: 1 M NaOH: soluble 50 mg/mL
antibiotic activity spectrum: Gram-negative bacteriaGram-positive bacteriamycobacteria
Mode of action: DNA synthesis | interferesenzyme | inhibits
storage temp.: 2-8°C
InChI: 1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)
InChI key: GSDSWSVVBLHKDQ-UHFFFAOYSA-N
biological source:
synthetic
Quality Level:
200
Assay:
≥99% (HPLC)
form:
powder
solubility:
1 M NaOH: soluble 50 mg/mL
antibiotic activity spectrum:
Gram-negative bacteriaGram-positive bacteriamycobacteria
Mode of action:
DNA synthesis | interferesenzyme | inhibits
storage temp.:
2-8°C
InChI:
1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)
InChI key:
GSDSWSVVBLHKDQ-UHFFFAOYSA-N
biological source: __
Quality Level: 200
Assay: ≥98% (TLC)
form: powder
solubility: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: −20°C
InChI: 1S/C14H23NO4/c1-2-3-4-5-6-7-11(16)10-13(17)15-12-8-9-19-14(12)18/h12H,2-10H2,1H3,(H,15,17)/t12-/m0/s1
InChI key: KYGIKEQVUKTKRR-LBPRGKRZSA-N
biological source:
__
Quality Level:
200
Assay:
≥98% (TLC)
form:
powder
solubility:
__
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
−20°C
InChI:
1S/C14H23NO4/c1-2-3-4-5-6-7-11(16)10-13(17)15-12-8-9-19-14(12)18/h12H,2-10H2,1H3,(H,15,17)/t12-/m0/s1
InChI key:
KYGIKEQVUKTKRR-LBPRGKRZSA-N
biological source: __
Quality Level: 200
Assay: ≥98% (TLC)
form: powder
solubility: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: −20°C
InChI: 1S/C16H27NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14H,2-12H2,1H3,(H,17,19)/t14-/m0/s1
InChI key: PHSRRHGYXQCRPU-AWEZNQCLSA-N
biological source:
__
Quality Level:
200
Assay:
≥98% (TLC)
form:
powder
solubility:
__
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
−20°C
InChI:
1S/C16H27NO4/c1-2-3-4-5-6-7-8-9-13(18)12-15(19)17-14-10-11-21-16(14)20/h14H,2-12H2,1H3,(H,17,19)/t14-/m0/s1
InChI key:
PHSRRHGYXQCRPU-AWEZNQCLSA-N
biological source: __
Quality Level: 200
Assay: ≥98% (TLC)
form: powder
solubility: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: −20°C
InChI: 1S/C18H31NO4/c1-2-3-4-5-6-7-8-9-10-11-15(20)14-17(21)19-16-12-13-23-18(16)22/h16H,2-14H2,1H3,(H,19,21)/t16-/m0/s1
InChI key: YQFJJDSGBAAUPW-INIZCTEOSA-N
biological source:
__
Quality Level:
200
Assay:
≥98% (TLC)
form:
powder
solubility:
__
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
−20°C
InChI:
1S/C18H31NO4/c1-2-3-4-5-6-7-8-9-10-11-15(20)14-17(21)19-16-12-13-23-18(16)22/h16H,2-14H2,1H3,(H,19,21)/t16-/m0/s1
InChI key:
YQFJJDSGBAAUPW-INIZCTEOSA-N