Pefloxacin mesylate dihydrate
Manufacturer: Sigma Aldrich
CAS Number: 149676-40-4
Synonym(S): 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-, monomethanesulfonate, dihydrate, Pefloxacine monomethanesulfonate dihydrate, Pefloxacinium methanesulfonate dihydrate
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 G | P0106-10-G | In Stock | ₹ 8,424.90 |
P0106 - 10 G
In Stock
Quantity
1
Base Price: ₹ 8,424.90
GST (18%): ₹ 1,516.482
Total Price: ₹ 9,941.382
form
powder
Quality Level
100
solubility
H2O: 50 mg/mL
antibiotic activity spectrum
Gram-negative bacteriaGram-positive bacteria
Mode of action
DNA synthesis | interferesenzyme | inhibits
storage temp.
2-8°C
SMILES string
O.O.CS(O)(=O)=O.CCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCN(C)CC3
InChI
1S/C17H20FN3O3.CH4O3S.2H2O/c1-3-20-10-12(17(23)24)16(22)11-8-13(18)15(9-14(11)20)21-6-4-19(2)5-7-21;1-5(2,3)4;;/h8-10H,3-7H2,1-2H3,(H,23,24);1H3,(H,2,3,4);2*1H2
InChI key
LEULAXMUNMRLPW-UHFFFAOYSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Apexbio Technology LLC Pefloxacin Mesylate Dihydrate, 10g. Cas: 149676-40-4 MFCD: MFCD01685696. third generation of fluoroquinolone class of antibacterials | Apexbio Technology LLC | ₹ 4,834.14 | |
 | Sigma Aldrich Fine Chemicals Biosciences Pefloxacin mesylate dihydrate | 149676-40-4 | MFCD01685696 | 10G | Sigma Aldrich Fine Chemicals Biosciences | ₹ 8,059.75 | |
 | Pefloxacin mesilate dihydrate | Sigma Aldrich | ₹ 14,629.80 | |
 | 149676-40-4 | 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID | A2B Chem | ₹ 1,197.84 - ₹ 3,507.96 |
Related Products
Description
- General description: Chemical structure: fluoroquinolone
- Application: Pefloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic that is effective against most gram-negative and gram-positive bacteria. It is used to treat gonococcal urethritis and for gram-negative-bacterial infections in the gastrointestinal system and the genitourinary tract. Pefloxacin mesylate dihydrate has been used to induce achilles tendon toxicity in rodents[1]. It′s cytotoxicity and uptake have been studied in primary cultures of rat hepatocytes[2].
- Biochem/physiol Actions: Pefloxacin inhibits the bacterial enzymes DNA gyrase and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase is thought to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV is thought to be the primary target in gram-positive organisms. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited . Pefloxacin is an analog of norfloxacin.
- Other Notes: Keep container tightly closed in a dry and well-ventilated place.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
form: powder
Quality Level: 100
solubility: H2O: 50 mg/mL
antibiotic activity spectrum: Gram-negative bacteriaGram-positive bacteria
Mode of action: DNA synthesis | interferesenzyme | inhibits
storage temp.: 2-8°C
SMILES string: O.O.CS(O)(=O)=O.CCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCN(C)CC3
InChI: 1S/C17H20FN3O3.CH4O3S.2H2O/c1-3-20-10-12(17(23)24)16(22)11-8-13(18)15(9-14(11)20)21-6-4-19(2)5-7-21;1-5(2,3)4;;/h8-10H,3-7H2,1-2H3,(H,23,24);1H3,(H,2,3,4);2*1H2
InChI key: LEULAXMUNMRLPW-UHFFFAOYSA-N
form: powder
Quality Level: 200
solubility: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: 2-8°C
SMILES string: __
InChI: __
InChI key: __
form: buffered aqueous solution
Quality Level: 200
solubility: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: __
SMILES string: __
InChI: __
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