E4632

Econazole nitrate salt

Manufacturer: Sigma Aldrich

CAS Number: 24169-02-6

Synonym(S): 1-(2-[(4-Chlorophenyl)methoxy]-2-[2,4-dichlorophenyl]ethyl)-1H-imidazole

Select a Size

Pack Size SKU Availability Price
5 G E4632-5-G In Stock ₹ 9,244.55
25 G E4632-25-G In Stock ₹ 29,725.45
100 G E4632-100-G In Stock ₹ 57,210.13

E4632 - 5 G

₹ 9,244.55

In Stock

Quantity

1

Base Price: ₹ 9,244.55

GST (18%): ₹ 1,664.019

Total Price: ₹ 10,908.569

form

powder or crystals

Quality Level

200

color

white to off-white

antibiotic activity spectrum

Gram-positive bacteriafungi

Mode of action

cell membrane | interferescell wall synthesis | interferesenzyme | inhibits

SMILES string

O[N+]([O-])=O.Clc1ccc(COC(Cn2ccnc2)c3ccc(Cl)cc3Cl)cc1

InChI

1S/C18H15Cl3N2O.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)

InChI key

DDXORDQKGIZAME-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
50-532-9
Selleck Chemical LLC Econazole nitrate 50mg 24169-02-6 NSC 243115
Selleck Chemical LLC ₹ 9,959.18
50-179-3495
Sigma Aldrich Fine Chemicals Biosciences Econazole nitrate salt | 24169-02-6 | MFCD00058160 | 5G
Sigma Aldrich Fine Chemicals Biosciences ₹ 8,188.09
E4632
Econazole nitrate salt
Sigma Aldrich ₹ 9,244.55 - ₹ 57,210.13
CS-2564
Econazole (nitrate)
ChemScene ₹ 4,278.00
AI45633
24169-02-6 | 1-{2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole; nitric acid
A2B Chem ₹ 1,026.72 - ₹ 34,224.00

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Description

  • General description: Chemical structure: imidazole
  • Application: Econazole is a broad spectrum antimycotic similar to ketoconazole. It has some action against Gram positive bacteria. It is used topically in dermatomycoses as well as orally and parenterally. It is used for studies on processes such as platelet serotonin uptake, prostanoid biosynthesis, EDHF-mediated relaxation, and Ca2+ transport pathways in thymic lymphocytes[1].
  • Biochem/physiol Actions: Econazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. Inhibition of ergosterol results in increased cellular permeability causing leakage of cellular contents. Econazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and phospholipid biosynthesis.

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319

Precautionary Statements

P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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E4632

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form:
powder or crystals

Quality Level:
200

color:
white to off-white

antibiotic activity spectrum:
Gram-positive bacteriafungi

Mode of action:
cell membrane | interferescell wall synthesis | interferesenzyme | inhibits

SMILES string:
O[N+]([O-])=O.Clc1ccc(COC(Cn2ccnc2)c3ccc(Cl)cc3Cl)cc1

InChI:
1S/C18H15Cl3N2O.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)

InChI key:
DDXORDQKGIZAME-UHFFFAOYSA-N

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InChI key:
FMVJYQGSRWVMQV-UHFFFAOYSA-N