917397
(2-(Piperidin-4-yl)phenyl)methanamine dihydrochloride
Manufacturer: Sigma Aldrich
CAS Number: 2244085-89-8
Synonym(S): Semi-flexible linker for PROTAC® development
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | 917397-100-MG | In Stock | ₹ 23,934.08 |
917397 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 23,934.08
GST (18%): ₹ 4,308.134
Total Price: ₹ 28,242.214
form
powder
Quality Level
100
reaction suitability
reagent type: linker
functional group
amine
storage temp.
2-8°C
SMILES string
NCC1=C(C=CC=C1)C2CCNCC2.Cl.Cl
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | (2-(Piperidin-4-yl)phenyl)methanamine dihydrochloride | ChemScene | ₹ 12,406.20 - ₹ 68,448.00 | |
 | 2244085-89-8 | (2-(Piperidin-4-yl)phenyl)methanamine dihydrochloride | A2B Chem | ₹ 8,727.12 - ₹ 47,913.60 |
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Description
- Application: (2-(Piperidin-4-yl)phenyl)methanamine dihydrochloride is a 4-aryl piperidine useful as a semi-flexible linker in PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties.
- Other Notes: Portal: Building PROTAC® Degraders for Targeted Protein DegradationCrosslinkers for BioconjugationTechnology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
- Legal Information: PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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form: powder
Quality Level: 100
reaction suitability: reagent type: linker
functional group: amine
storage temp.: 2-8°C
SMILES string: NCC1=C(C=CC=C1)C2CCNCC2.Cl.Cl
form:
powder
Quality Level:
100
reaction suitability:
reagent type: linker
functional group:
amine
storage temp.:
2-8°C
SMILES string:
NCC1=C(C=CC=C1)C2CCNCC2.Cl.Cl
form: powder
Quality Level: 100
reaction suitability: reagent type: linker
functional group: Bochydroxyl
storage temp.: 2-8°C
SMILES string: O=C(N(CC1)CCC1C2=CC(CO)=CC=C2)OC(C)(C)C
form:
powder
Quality Level:
100
reaction suitability:
reagent type: linker
functional group:
Bochydroxyl
storage temp.:
2-8°C
SMILES string:
O=C(N(CC1)CCC1C2=CC(CO)=CC=C2)OC(C)(C)C
form: liquid
Quality Level: 200
reaction suitability: __
functional group: __
storage temp.: __
SMILES string: C[Si](C)(C)OS(=O)(=O)C(F)(F)F
form:
liquid
Quality Level:
200
reaction suitability:
__
functional group:
__
storage temp.:
__
SMILES string:
C[Si](C)(C)OS(=O)(=O)C(F)(F)F
form: powder
Quality Level: 100
reaction suitability: reagent type: linker
functional group: amine
storage temp.: 2-8°C
SMILES string: NCCC1=C(C=CC=C1)C2CCNCC2.Cl.Cl
form:
powder
Quality Level:
100
reaction suitability:
reagent type: linker
functional group:
amine
storage temp.:
2-8°C
SMILES string:
NCCC1=C(C=CC=C1)C2CCNCC2.Cl.Cl