K1443
Thermo Scientific™ Tango™ AGTR1-blaU2OS Cells
Manufacturer: Thermo Scientific™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | K1443-Each-of-1 | In Stock | ₹ 9,05,224.80 |
K1443 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 9,05,224.80
GST (18%): ₹ 1,62,940.464
Total Price: ₹ 10,68,165.264
Accession Number
NM_032049.2
Cell State
Dividing Cells
Cytoplasmic Tail
Native Tail
For Use With (Application)
FRET
Human Protein Class
G-Protein Coupled Receptor (GPCR)
Product Line
Tango™
Readout
End Point
Target Entry
AGTR1
System Type
Tango™
Assay Entry
Cell-based beta-arrestin recruitment
Content And Storage
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ AGTR1-UAS-bla CHO-K1 cells• Tango™ AGTR1-UAS-bla CHO-K1 Assay Protocol• Certificate of AnalysisThe Tango™ AGTR1-UAS-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method
Fluorescence
Gene Symbol
AGTR1
Population Status
Single Cell Clone Origin
Quantity
8 x 106Cells
Shipping Condition
Room Temperature
Cell Line
U2OS
Druggable Target
GPCR
Related Products
Description
- Tango™ AGTR1-bla U2OS cells contain the human Angiotensin Receptor 1 (AGTR1) (AGTR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line
- This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element
- The Tango™ AGTR1-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of Angiotensin II (Figure 1)
- In addition, Tango™ AGTR1-bla U2OS cells have been tested for assay performance under variable conditions.
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Accession Number: NM_032049.2
Cell State: Dividing Cells
Cytoplasmic Tail: Native Tail
For Use With (Application): FRET
Human Protein Class: G-Protein Coupled Receptor (GPCR)
Product Line: Tango™
Readout: End Point
Target Entry: AGTR1
System Type: Tango™
Assay Entry: Cell-based beta-arrestin recruitment
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ AGTR1-UAS-bla CHO-K1 cells• Tango™ AGTR1-UAS-bla CHO-K1 Assay Protocol• Certificate of AnalysisThe Tango™ AGTR1-UAS-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method: Fluorescence
Gene Symbol: AGTR1
Population Status: Single Cell Clone Origin
Quantity: 8 x 106Cells
Shipping Condition: Room Temperature
Cell Line: U2OS
Druggable Target: GPCR
Accession Number:
NM_032049.2
Cell State:
Dividing Cells
Cytoplasmic Tail:
Native Tail
For Use With (Application):
FRET
Human Protein Class:
G-Protein Coupled Receptor (GPCR)
Product Line:
Tango™
Readout:
End Point
Target Entry:
AGTR1
System Type:
Tango™
Assay Entry:
Cell-based beta-arrestin recruitment
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ AGTR1-UAS-bla CHO-K1 cells• Tango™ AGTR1-UAS-bla CHO-K1 Assay Protocol• Certificate of AnalysisThe Tango™ AGTR1-UAS-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method:
Fluorescence
Gene Symbol:
AGTR1
Population Status:
Single Cell Clone Origin
Quantity:
8 x 106Cells
Shipping Condition:
Room Temperature
Cell Line:
U2OS
Druggable Target:
GPCR
Accession Number: NM_001957
Cell State: Dividing Cells
Cytoplasmic Tail: Tail from AVPR2 GPCR
For Use With (Application): __
Human Protein Class: __
Product Line: Tango™
Readout: __
Target Entry: EDNRA
System Type: Tango™
Assay Entry: Cell-based beta-arrestin recruitment
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ EDNRA-bla U2OS cells• Tango™ EDNRA-bla U2OS Assay Protocol• Certificate of AnalysisTango™ EDNRA-bla U2OS cells are shipped on dry ice. Transfer to liquid nitrogen immediately upon receipt or thaw for immediate use.
Detection Method: Fluorescence
Gene Symbol: EDNRA
Population Status: Pool of Stable Cells
Quantity: 2 x 106Cells
Shipping Condition: Room Temperature
Cell Line: U2OS
Druggable Target: GPCR
Accession Number:
NM_001957
Cell State:
Dividing Cells
Cytoplasmic Tail:
Tail from AVPR2 GPCR
For Use With (Application):
__
Human Protein Class:
__
Product Line:
Tango™
Readout:
__
Target Entry:
EDNRA
System Type:
Tango™
Assay Entry:
Cell-based beta-arrestin recruitment
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ EDNRA-bla U2OS cells• Tango™ EDNRA-bla U2OS Assay Protocol• Certificate of AnalysisTango™ EDNRA-bla U2OS cells are shipped on dry ice. Transfer to liquid nitrogen immediately upon receipt or thaw for immediate use.
Detection Method:
Fluorescence
Gene Symbol:
EDNRA
Population Status:
Pool of Stable Cells
Quantity:
2 x 106Cells
Shipping Condition:
Room Temperature
Cell Line:
U2OS
Druggable Target:
GPCR
Accession Number: NM_000674.1
Cell State: Dividing Cells
Cytoplasmic Tail: Tail from AVPR2 GPCR
For Use With (Application): __
Human Protein Class: __
Product Line: Tango™
Readout: __
Target Entry: ADORA1
System Type: Tango™
Assay Entry: Cell-based beta-arrestin recruitment
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ ADORA1-bla U2OS cells• Tango™ ADORA1-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ ADORA1-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method: Fluorescence
Gene Symbol: ADORA1A
Population Status: Pool of Stable Cells
Quantity: 2 x 106Cells
Shipping Condition: __
Cell Line: U2OS
Druggable Target: GPCR
Accession Number:
NM_000674.1
Cell State:
Dividing Cells
Cytoplasmic Tail:
Tail from AVPR2 GPCR
For Use With (Application):
__
Human Protein Class:
__
Product Line:
Tango™
Readout:
__
Target Entry:
ADORA1
System Type:
Tango™
Assay Entry:
Cell-based beta-arrestin recruitment
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ ADORA1-bla U2OS cells• Tango™ ADORA1-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ ADORA1-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method:
Fluorescence
Gene Symbol:
ADORA1A
Population Status:
Pool of Stable Cells
Quantity:
2 x 106Cells
Shipping Condition:
__
Cell Line:
U2OS
Druggable Target:
GPCR
Accession Number: __
Cell State: __
Cytoplasmic Tail: __
For Use With (Application): __
Human Protein Class: __
Product Line: __
Readout: __
Target Entry: __
System Type: __
Assay Entry: __
Content And Storage: The β-Gal Assay Kit contains 10X PBS (phosphate buffered saline), lysis buffer, cleavage buffer, β-mercaptoethanol, ONPG, stop buffer. Store ONPG at -20°C. All other components are stored at either room temperature or +4°C. All reagents are guaranteed stable for 6 months when properly stored.
Detection Method: Colorimetric
Gene Symbol: __
Population Status: __
Quantity: 80 mL
Shipping Condition: __
Cell Line: __
Druggable Target: __
Accession Number:
__
Cell State:
__
Cytoplasmic Tail:
__
For Use With (Application):
__
Human Protein Class:
__
Product Line:
__
Readout:
__
Target Entry:
__
System Type:
__
Assay Entry:
__
Content And Storage:
The β-Gal Assay Kit contains 10X PBS (phosphate buffered saline), lysis buffer, cleavage buffer, β-mercaptoethanol, ONPG, stop buffer. Store ONPG at -20°C. All other components are stored at either room temperature or +4°C. All reagents are guaranteed stable for 6 months when properly stored.
Detection Method:
Colorimetric
Gene Symbol:
__
Population Status:
__
Quantity:
80 mL
Shipping Condition:
__
Cell Line:
__
Druggable Target:
__