K1857
Thermo Scientific™ Tango™ HTR1A-blaU2OS Cells
Manufacturer: Thermo Scientific™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | K1857-Each-of-1 | In Stock | ₹ 9,05,224.80 |
K1857 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 9,05,224.80
GST (18%): ₹ 1,62,940.464
Total Price: ₹ 10,68,165.264
Accession Number
NM_000524
Cell State
Dividing Cells
Cytoplasmic Tail
Tail from AVPR2 GPCR
For Use With (Application)
FRET
Human Protein Class
G-Protein Coupled Receptor (GPCR)
Product Line
Tango™
Readout
End Point
Cell Line
U2OS
Druggable Target
GPCR
Assay Entry
Cell-based beta-arrestin recruitment
Content And Storage
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ HTR1A-UAS-bla CHO-K1 cells• Tango™ HTR1A-UAS-bla CHO-K1 Assay Protocol• Certificate of AnalysisThe Tango™ HTR1A-UAS-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method
Fluorescence
Gene Symbol
HTR1A
Population Status
Single Cell Clone Origin
Quantity
8 x 106Cells
Target Entry
5HT1A, HTR1A
System Type
Tango™
Related Products
Description
- Tango™ HTR1A-bla U2OS cells contain the human Serotonin Type 1a receptor (HTR1A) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line
- This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element
- Tango™ HTR1A-bla U2OS DA cells have been functionally validated for Z' factor and EC50 concentrations of 5-CT (Figure 1)
- In addition, Tango™ HTR1A-bla U2OS cells have been tested for assay performance under variable conditions.
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Accession Number: NM_000524
Cell State: Dividing Cells
Cytoplasmic Tail: Tail from AVPR2 GPCR
For Use With (Application): FRET
Human Protein Class: G-Protein Coupled Receptor (GPCR)
Product Line: Tango™
Readout: End Point
Cell Line: U2OS
Druggable Target: GPCR
Assay Entry: Cell-based beta-arrestin recruitment
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ HTR1A-UAS-bla CHO-K1 cells• Tango™ HTR1A-UAS-bla CHO-K1 Assay Protocol• Certificate of AnalysisThe Tango™ HTR1A-UAS-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method: Fluorescence
Gene Symbol: HTR1A
Population Status: Single Cell Clone Origin
Quantity: 8 x 106Cells
Target Entry: 5HT1A, HTR1A
System Type: Tango™
Accession Number:
NM_000524
Cell State:
Dividing Cells
Cytoplasmic Tail:
Tail from AVPR2 GPCR
For Use With (Application):
FRET
Human Protein Class:
G-Protein Coupled Receptor (GPCR)
Product Line:
Tango™
Readout:
End Point
Cell Line:
U2OS
Druggable Target:
GPCR
Assay Entry:
Cell-based beta-arrestin recruitment
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ HTR1A-UAS-bla CHO-K1 cells• Tango™ HTR1A-UAS-bla CHO-K1 Assay Protocol• Certificate of AnalysisThe Tango™ HTR1A-UAS-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method:
Fluorescence
Gene Symbol:
HTR1A
Population Status:
Single Cell Clone Origin
Quantity:
8 x 106Cells
Target Entry:
5HT1A, HTR1A
System Type:
Tango™
Accession Number: NM_014879.2
Cell State: Dividing Cells
Cytoplasmic Tail: Native Tail
For Use With (Application): FRET
Human Protein Class: G-Protein Coupled Receptor (GPCR)
Product Line: Tango™
Readout: End Point
Cell Line: U2OS
Druggable Target: GPCR
Assay Entry: Cell-based beta-arrestin recruitment
Content And Storage: Tango™ cell lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Detection Method: Fluorescence
Gene Symbol: __
Population Status: Single Cell Clone Origin
Quantity: 8 x 106Cells
Target Entry: P2RY14
System Type: Tango™
Accession Number:
NM_014879.2
Cell State:
Dividing Cells
Cytoplasmic Tail:
Native Tail
For Use With (Application):
FRET
Human Protein Class:
G-Protein Coupled Receptor (GPCR)
Product Line:
Tango™
Readout:
End Point
Cell Line:
U2OS
Druggable Target:
GPCR
Assay Entry:
Cell-based beta-arrestin recruitment
Content And Storage:
Tango™ cell lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Detection Method:
Fluorescence
Gene Symbol:
__
Population Status:
Single Cell Clone Origin
Quantity:
8 x 106Cells
Target Entry:
P2RY14
System Type:
Tango™
Accession Number: NM_004778
Cell State: Dividing Cells
Cytoplasmic Tail: Tail from GRPR GPCR
For Use With (Application): FRET
Human Protein Class: G-Protein Coupled Receptor (GPCR)
Product Line: Tango™
Readout: End Point
Cell Line: U2OS
Druggable Target: GPCR
Assay Entry: Cell-based beta-arrestin recruitment
Content And Storage: Tango™ GPR44 (CRTH2)-bla U2OS cells are shipped on dry ice, 8 x 106cells/vial. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Detection Method: Fluorescence
Gene Symbol: __
Population Status: Single Cell Clone Origin
Quantity: 1 Vial
Target Entry: CRTH2, GPR44
System Type: Tango™
Accession Number:
NM_004778
Cell State:
Dividing Cells
Cytoplasmic Tail:
Tail from GRPR GPCR
For Use With (Application):
FRET
Human Protein Class:
G-Protein Coupled Receptor (GPCR)
Product Line:
Tango™
Readout:
End Point
Cell Line:
U2OS
Druggable Target:
GPCR
Assay Entry:
Cell-based beta-arrestin recruitment
Content And Storage:
Tango™ GPR44 (CRTH2)-bla U2OS cells are shipped on dry ice, 8 x 106cells/vial. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Detection Method:
Fluorescence
Gene Symbol:
__
Population Status:
Single Cell Clone Origin
Quantity:
1 Vial
Target Entry:
CRTH2, GPR44
System Type:
Tango™
Accession Number: __
Cell State: __
Cytoplasmic Tail: __
For Use With (Application): __
Human Protein Class: __
Product Line: __
Readout: __
Cell Line: __
Druggable Target: __
Assay Entry: __
Content And Storage: __
Detection Method: __
Gene Symbol: __
Population Status: __
Quantity: __
Target Entry: __
System Type: __
Accession Number:
__
Cell State:
__
Cytoplasmic Tail:
__
For Use With (Application):
__
Human Protein Class:
__
Product Line:
__
Readout:
__
Cell Line:
__
Druggable Target:
__
Assay Entry:
__
Content And Storage:
__
Detection Method:
__
Gene Symbol:
__
Population Status:
__
Quantity:
__
Target Entry:
__
System Type:
__