K1467

Invitrogen™ CellSensor™ Myc-blaHCT116 Cell Line

Manufacturer: Invitrogen™

Select a Size

Pack Size SKU Availability Price
Each of 1 K1467-Each-of-1 In Stock ₹ 8,80,412.40

K1467 - Each of 1

₹ 8,80,412.40

In Stock

Quantity

1

Base Price: ₹ 8,80,412.40

GST (18%): ₹ 1,58,474.232

Total Price: ₹ 10,38,886.632

Assay Entry

Cell-based beta lactamase reporter gene

Content And Storage

CellSensor™ Myc-bla HCT116 cells are shipped on dry ice.Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.

Product Line

CellSensor™

Target Entry

Myc pathway, MYC

Cell Line

HCT-116

Druggable Target

Signaling Pathway

Cell State

Dividing Cells

Detection Method

Fluorescence

Quantity

1 vial

Type

Cell Line

System Type

CellSensor™

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Description

  • The CellSensor™Myc- bla HCT116 cell line contains a beta-lactamase reporter gene under the control of Myc binding sequences
  • The construct was transduced into HCT116 cells using a lentiviral system
  • HCT116 is a colon cancer cell line which expresses a mutated form of beta-catenin
  • This form of beta-catenin leads to the accumulation of beta-catenin and constitutive activation of downstream genes such as Myc
  • This cell line is a clonal population isolated by flow cytometry
  • It has been validated for cell plating density and DMSO tolerance
  • The signaling pathway has been validated using RNAi against c-Myc and ICG-001, an inhibitor of the wnt-beta-catenin pathway
  • The expression of the mutant beta-catenin in HCT116 cells results in constitutive activation of beta-lactamase in this CellSensor™line, which can be knocked down by ICG-001 (Figure 1) or Myc RNAi (Figure 2).

Compare Similar Items

Show Difference

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Invitrogen™

K1467

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Assay Entry:
Cell-based beta lactamase reporter gene

Content And Storage:
CellSensor™ Myc-bla HCT116 cells are shipped on dry ice.Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.

Product Line:
CellSensor™

Target Entry:
Myc pathway, MYC

Cell Line:
HCT-116

Druggable Target:
Signaling Pathway

Cell State:
Dividing Cells

Detection Method:
Fluorescence

Quantity:
1 vial

Type:
Cell Line

System Type:
CellSensor™

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Thermo Scientific™

K1469

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Assay Entry:
Cell-based terbium phospho-specific activity (stable)

Content And Storage:
LanthaScreen™ STAT1 U2OS cells are shipped on dry ice.Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.

Product Line:
LanthaScreen™

Target Entry:
STAT1

Cell Line:
__

Druggable Target:
Signaling Pathway

Cell State:
Dividing Cells

Detection Method:
__

Quantity:
1 Vial

Type:
__

System Type:
LanthaScreen™

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Thermo Scientific™

K1470

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Assay Entry:
Cell-based beta lactamase reporter gene

Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ ADRA1A -NFAT-bla CHO-K1 cells• GeneBLAzer™ ADRA1A -NFAT-bla CHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ ADRA1A -NFAT-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Product Line:
GeneBLAzer™

Target Entry:
ADRA1A

Cell Line:
CHO-K1

Druggable Target:
GPCR

Cell State:
Dividing Cells

Detection Method:
Fluorescence

Quantity:
2 x 106cells

Type:
CHO-K1 Cells

System Type:
GeneBLAzer™

Img

Thermo Scientific™

K1471

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Assay Entry:
Cell-based beta lactamase reporter gene

Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ ADRA1B-NFAT-bla CHO-K1 cells• GeneBLAzer™ ADRA1B-NFAT-bla CHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ ADRA1B-NFAT-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Product Line:
GeneBLAzer™

Target Entry:
ADRA1B

Cell Line:
CHO-K1

Druggable Target:
GPCR

Cell State:
Dividing Cells

Detection Method:
Fluorescence

Quantity:
2 x 106Cells

Type:
CHO-K1 Cells

System Type:
GeneBLAzer™