Thermo Scientific™ Tango™ CCR1-blaU2OS DA Assay Kit
Manufacturer: Thermo Scientific™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | K1793-Each-of-1 | In Stock | ₹ 98,736.24 |
K1793 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 98,736.24
GST (18%): ₹ 17,772.523
Total Price: ₹ 1,16,508.763
Accession Number
NM_001295
Cell State
Division-Arrested Cells
Cytoplasmic Tail
Tail from GRPR GPCR
Gene Symbol
CCR1
Product Line
GeneBLAzer™
Quantity
1 Kit
Reporter Gene
BLA (Beta-Lactamase)
Cell Line
U2OS
Druggable Target
GPCR
Assay Entry
Cell-based beta-arrestin recruitment
Content And Storage
Each kit contains sufficient quantities of division arrested (DA) cells and substrate to assay 1 x 384 well plate. (Other materials are required separately; please refer to the protocol).Includes:• Tango™ CCR1-bla U2OS DA cells• LiveBLAzer™-FRET B/G Loading Kit, 70 μg• Solution D• Tango™ CCR1-bla U2OS DA Assay Protocol• LiveBLAzer™-FRET B/G Loading Protocol• Certificate of AnalysisThe Tango™ CCR1-bla U2OS DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method
Fluorescence
Population Status
Single Cell Clone Origin
Protein Family
GPCR (G-Protein Coupled Receptors)
Readout
End Point
Target Entry
CCR1
System Type
Tango™
Related Products
Description
- The Tango™ CCR1-bla U2OS DA cells contain the human Chemokine (C-C Motif) Receptor 1 (CCR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line
- This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element
- The Tango™ CCR1-bla U2OS DA cells have been functionally validated for Z' factor and EC50 concentrations of established ligands
- In addition, Tango™ CCR1-bla U2OS DA cells have been tested for assay performance under variable conditions
- These data are found in the Validation & Assay Performance Summary for each product
- Division Arrested cells are irreversibly division arrested using a low-dose treatment of Mitomycin C, and have no apparent toxicity or change in cellular signal transduction.
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Accession Number: NM_001295
Cell State: Division-Arrested Cells
Cytoplasmic Tail: Tail from GRPR GPCR
Gene Symbol: CCR1
Product Line: GeneBLAzer™
Quantity: 1 Kit
Reporter Gene: BLA (Beta-Lactamase)
Cell Line: U2OS
Druggable Target: GPCR
Assay Entry: Cell-based beta-arrestin recruitment
Content And Storage: Each kit contains sufficient quantities of division arrested (DA) cells and substrate to assay 1 x 384 well plate. (Other materials are required separately; please refer to the protocol).Includes:• Tango™ CCR1-bla U2OS DA cells• LiveBLAzer™-FRET B/G Loading Kit, 70 μg• Solution D• Tango™ CCR1-bla U2OS DA Assay Protocol• LiveBLAzer™-FRET B/G Loading Protocol• Certificate of AnalysisThe Tango™ CCR1-bla U2OS DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method: Fluorescence
Population Status: Single Cell Clone Origin
Protein Family: GPCR (G-Protein Coupled Receptors)
Readout: End Point
Target Entry: CCR1
System Type: Tango™
Accession Number: __
Cell State: __
Cytoplasmic Tail: __
Gene Symbol: __
Product Line: __
Quantity: __
Reporter Gene: __
Cell Line: __
Druggable Target: __
Assay Entry: __
Content And Storage: __
Detection Method: __
Population Status: __
Protein Family: __
Readout: __
Target Entry: __
System Type: __
Accession Number: __
Cell State: __
Cytoplasmic Tail: __
Gene Symbol: __
Product Line: __
Quantity: __
Reporter Gene: __
Cell Line: __
Druggable Target: __
Assay Entry: __
Content And Storage: __
Detection Method: __
Population Status: __
Protein Family: __
Readout: __
Target Entry: __
System Type: __