K1765

Thermo Scientific™ Tango™ CCR6-blaU2OS DA Assay Kit

Manufacturer: Thermo Scientific™

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Pack Size SKU Availability Price
Each of 1 K1765-Each-of-1 In Stock ₹ 97,709.52

K1765 - Each of 1

₹ 97,709.52

In Stock

Quantity

1

Base Price: ₹ 97,709.52

GST (18%): ₹ 17,587.714

Total Price: ₹ 1,15,297.234

Accession Number

NM_004367.3

Cell State

Division-Arrested Cells

Cytoplasmic Tail

Native Tail

Gene Symbol

CCR6

Product Line

Tango™

Reporter Gene

BLA (Beta-Lactamase)

Cell Line

U2OS

Druggable Target

GPCR

Assay Entry

Cell-based beta-arrestin recruitment

Content And Storage

Each kit contains sufficient quantities of division arrested (DA) cells and substrate to assay 1 x 384 well plate. (Other materials are required separately; please refer to the protocol).Includes:• Tango™ CCR6-bla U2OS DA cells• LiveBLAzer™-FRET B/G Loading Kit, 70 μg• Solution D• Tango™ CCR6-bla U2OS DA Assay Protocol• LiveBLAzer™-FRET B/G Loading Protocol• Certificate of AnalysisThe Tango™ CCR6-bla U2OS DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method

Fluorescence

Population Status

Single Cell Clone Origin

Quantity

8 x 106Cells

Target Entry

CCR6

System Type

Tango™

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Description

  • The Tango™ CCR6-bla U2OS cells contain the human Chemokine (C-C motif) Receptor 6 (CCR6) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line
  • This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element
  • The Tango™ CCR6-bla U2OS cells cells have been functionally validated for Z' factor and EC50 concentrations of established ligands
  • In addition, Tango™ CCR6-bla U2OS cells have been tested for assay performance under variable conditions
  • These data are found in the Validation & Assay Performance Summary for each product
  • Division Arrested cells are irreversibly division arrested using a low-dose treatment of Mitomycin C, and have no apparent toxicity or change in cellular signal transduction.

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Thermo Scientific™

K1765

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Accession Number:
NM_004367.3

Cell State:
Division-Arrested Cells

Cytoplasmic Tail:
Native Tail

Gene Symbol:
CCR6

Product Line:
Tango™

Reporter Gene:
BLA (Beta-Lactamase)

Cell Line:
U2OS

Druggable Target:
GPCR

Assay Entry:
Cell-based beta-arrestin recruitment

Content And Storage:
Each kit contains sufficient quantities of division arrested (DA) cells and substrate to assay 1 x 384 well plate. (Other materials are required separately; please refer to the protocol).Includes:• Tango™ CCR6-bla U2OS DA cells• LiveBLAzer™-FRET B/G Loading Kit, 70 μg• Solution D• Tango™ CCR6-bla U2OS DA Assay Protocol• LiveBLAzer™-FRET B/G Loading Protocol• Certificate of AnalysisThe Tango™ CCR6-bla U2OS DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method:
Fluorescence

Population Status:
Single Cell Clone Origin

Quantity:
8 x 106Cells

Target Entry:
CCR6

System Type:
Tango™

Img

Thermo Scientific™

K1770

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Accession Number:
NM_178471.1

Cell State:
Division-Arrested Cells

Cytoplasmic Tail:
Native Tail

Gene Symbol:
GPR119

Product Line:
GeneBLAzer™

Reporter Gene:
BLA (Beta-Lactamase)

Cell Line:
U2OS

Druggable Target:
GPCR

Assay Entry:
Cell-based beta-arrestin recruitment

Content And Storage:
Each kit contains sufficient quantities of division arrested (DA) cells and substrate to assay 1 x 384 well plate. (Other materials are required separately; please refer to the protocol).Includes:• Tango™ GPR119-bla U2OS DA cells• LiveBLAzer™-FRET B/G Loading Kit, 70 μg• Solution D• Tango™ GPR119-bla U2OS DA Assay Protocol• LiveBLAzer™-FRET B/G Loading Protocol• Certificate of AnalysisThe Tango™ GPR119-bla U2OS DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method:
Fluorescence

Population Status:
Single Cell Clone Origin

Quantity:
1 Kit

Target Entry:
GPR119

System Type:
Tango™

Img

Thermo Scientific™

K1773

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Accession Number:
NM_002531

Cell State:
Division-Arrested Cells

Cytoplasmic Tail:
__

Gene Symbol:
NTSR1

Product Line:
GeneBLAzer™

Reporter Gene:
BLA (Beta-Lactamase)

Cell Line:
U2OS

Druggable Target:
GPCR

Assay Entry:
Cell-based beta lactamase reporter gene

Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ NTSR1 CHO-K1 DA cells• LiveBLAzer™-FRET B/G Loading Kit, 70 μg• Solution D• GeneBLAzer™ NTSR1 CHO-K1 DA Assay Protocol• LiveBLAzer™-FRET B/G Loading Protocol• Certificate of AnalysisThe GeneBLAzer™ NTSR1 CHO-K1 DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method:
Fluorescence

Population Status:
Pool of Stable Cells

Quantity:
1 Kit

Target Entry:
NTSR1

System Type:
GeneBLAzer™

Img

Thermo Scientific™

K1777

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Accession Number:
NM_178471.1

Cell State:
Dividing Cells

Cytoplasmic Tail:
Native Tail

Gene Symbol:
GPR119

Product Line:
GeneBLAzer™

Reporter Gene:
BLA (Beta-Lactamase)

Cell Line:
U2OS

Druggable Target:
GPCR

Assay Entry:
Cell-based beta-arrestin recruitment

Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• Tango™ GPR119-bla U2OS cells• Tango™ GPR119-bla U2OS Assay Protocol• Certificate of AnalysisThe Tango™ GPR119-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

Detection Method:
Fluorescence

Population Status:
Single Cell Clone Origin

Quantity:
8 x 106Cells

Target Entry:
GPR119

System Type:
Tango™