K1757
Thermo Scientific™ Tango™ EDG6-blaU2OS DA Assay Kit
Manufacturer: Thermo Scientific™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | K1757-Each-of-1 | In Stock | ₹ 1,00,276.32 |
K1757 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,00,276.32
GST (18%): ₹ 18,049.738
Total Price: ₹ 1,18,326.058
Accession Number
NM_003775.1
Cell State
Division-Arrested Cells
Cytoplasmic Tail
Tail from GRPR GPCR
Gene Symbol
EDG6
Product Line
Tango™
Reporter Gene
BLA (Beta-Lactamase)
Cell Line
U2OS
Druggable Target
GPCR
Assay Entry
Cell-based beta-arrestin recruitment
Content And Storage
Each kit contains sufficient quantities of division arrested (DA) cells and substrate to assay 1 x 384 well plate. (Other materials are required separately; please refer to the protocol).Includes:• Tango™ EDG6-bla U2OS DA cells• LiveBLAzer™-FRET B/G Loading Kit, 70μg• Solution D• Tango™ EDG6-bla U2OS DA Assay Protocol• LiveBLAzer™-FRET B/G Loading Protocol• Certificate of AnalysisThe Tango™ EDG6-bla U2OS DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method
Fluorescence
Population Status
Pool of Stable Cells
Quantity
8 x 106Cells
Target Entry
EDG6
System Type
Tango™
Related Products
Description
- The Tango™ EDG6-bla U2OS cells contain the human Endothelial Differentiation, Lysophosphatidic Acid G-protein-coupled Receptor, 6 (EDG6) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line
- This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element
- The Tango™ EDG6-bla U2OS cells cells have been functionally validated for Z' factor and EC50 concentrations of established ligands
- In addition, Tango™ EDG6-bla U2OS cells have been tested for assay performance under variable conditions
- These data are found in the Validation & Assay Performance Summary for each product
- Division Arrested cells are irreversibly division arrested using a low-dose treatment of Mitomycin C, and have no apparent toxicity or change in cellular signal transduction.
Compare Similar Items
Show Difference
Accession Number: NM_003775.1
Cell State: Division-Arrested Cells
Cytoplasmic Tail: Tail from GRPR GPCR
Gene Symbol: EDG6
Product Line: Tango™
Reporter Gene: BLA (Beta-Lactamase)
Cell Line: U2OS
Druggable Target: GPCR
Assay Entry: Cell-based beta-arrestin recruitment
Content And Storage: Each kit contains sufficient quantities of division arrested (DA) cells and substrate to assay 1 x 384 well plate. (Other materials are required separately; please refer to the protocol).Includes:• Tango™ EDG6-bla U2OS DA cells• LiveBLAzer™-FRET B/G Loading Kit, 70μg• Solution D• Tango™ EDG6-bla U2OS DA Assay Protocol• LiveBLAzer™-FRET B/G Loading Protocol• Certificate of AnalysisThe Tango™ EDG6-bla U2OS DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method: Fluorescence
Population Status: Pool of Stable Cells
Quantity: 8 x 106Cells
Target Entry: EDG6
System Type: Tango™
Accession Number:
NM_003775.1
Cell State:
Division-Arrested Cells
Cytoplasmic Tail:
Tail from GRPR GPCR
Gene Symbol:
EDG6
Product Line:
Tango™
Reporter Gene:
BLA (Beta-Lactamase)
Cell Line:
U2OS
Druggable Target:
GPCR
Assay Entry:
Cell-based beta-arrestin recruitment
Content And Storage:
Each kit contains sufficient quantities of division arrested (DA) cells and substrate to assay 1 x 384 well plate. (Other materials are required separately; please refer to the protocol).Includes:• Tango™ EDG6-bla U2OS DA cells• LiveBLAzer™-FRET B/G Loading Kit, 70μg• Solution D• Tango™ EDG6-bla U2OS DA Assay Protocol• LiveBLAzer™-FRET B/G Loading Protocol• Certificate of AnalysisThe Tango™ EDG6-bla U2OS DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method:
Fluorescence
Population Status:
Pool of Stable Cells
Quantity:
8 x 106Cells
Target Entry:
EDG6
System Type:
Tango™
Accession Number: NM_004367.3
Cell State: Dividing Cells
Cytoplasmic Tail: Native Tail
Gene Symbol: CCR6
Product Line: Tango™
Reporter Gene: BLA (Beta-Lactamase)
Cell Line: U2OS
Druggable Target: GPCR
Assay Entry: Cell-based beta-arrestin recruitment
Content And Storage: K1761 Tango™ CCR6-bla U2OS cells(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).Includes:• Tango™ CCR6-bla U2OS cells• Tango™ CCR6-bla U2OS Assay Protocol• Certificate of AnalysisStorage:The Tango™ CCR6-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method: Fluorescence
Population Status: Single Cell Clone Origin
Quantity: 2 x 106Cells
Target Entry: CCR6
System Type: Tango™
Accession Number:
NM_004367.3
Cell State:
Dividing Cells
Cytoplasmic Tail:
Native Tail
Gene Symbol:
CCR6
Product Line:
Tango™
Reporter Gene:
BLA (Beta-Lactamase)
Cell Line:
U2OS
Druggable Target:
GPCR
Assay Entry:
Cell-based beta-arrestin recruitment
Content And Storage:
K1761 Tango™ CCR6-bla U2OS cells(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).Includes:• Tango™ CCR6-bla U2OS cells• Tango™ CCR6-bla U2OS Assay Protocol• Certificate of AnalysisStorage:The Tango™ CCR6-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method:
Fluorescence
Population Status:
Single Cell Clone Origin
Quantity:
2 x 106Cells
Target Entry:
CCR6
System Type:
Tango™
Accession Number: NM_005161
Cell State: Division-Arrested Cells
Cytoplasmic Tail: Native Tail
Gene Symbol: AGTRL1
Product Line: GeneBLAzer™
Reporter Gene: BLA (Beta-Lactamase)
Cell Line: U2OS
Druggable Target: GPCR
Assay Entry: Cell-based beta-arrestin recruitment
Content And Storage: Each kit contains sufficient quantities of division arrested (DA) cells and substrate to assay 1 x 384 well plate. (Other materials are required separately; please refer to the protocol).Includes:• Tango™ AGTRL1-bla U2OS DA cells• LiveBLAzer™-FRET B/G Loading Kit, 70 μg• Solution D• Tango™ AGTRL1-bla U2OS DA Assay Protocol• LiveBLAzer™-FRET B/G Loading Protocol• Certificate of AnalysisThe Tango™ AGTRL1-bla U2OS DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method: Fluorescence
Population Status: Single Cell Clone Origin
Quantity: 1 Kit
Target Entry: AGTRL1
System Type: Tango™
Accession Number:
NM_005161
Cell State:
Division-Arrested Cells
Cytoplasmic Tail:
Native Tail
Gene Symbol:
AGTRL1
Product Line:
GeneBLAzer™
Reporter Gene:
BLA (Beta-Lactamase)
Cell Line:
U2OS
Druggable Target:
GPCR
Assay Entry:
Cell-based beta-arrestin recruitment
Content And Storage:
Each kit contains sufficient quantities of division arrested (DA) cells and substrate to assay 1 x 384 well plate. (Other materials are required separately; please refer to the protocol).Includes:• Tango™ AGTRL1-bla U2OS DA cells• LiveBLAzer™-FRET B/G Loading Kit, 70 μg• Solution D• Tango™ AGTRL1-bla U2OS DA Assay Protocol• LiveBLAzer™-FRET B/G Loading Protocol• Certificate of AnalysisThe Tango™ AGTRL1-bla U2OS DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method:
Fluorescence
Population Status:
Single Cell Clone Origin
Quantity:
1 Kit
Target Entry:
AGTRL1
System Type:
Tango™
Accession Number: NM_004367.3
Cell State: Division-Arrested Cells
Cytoplasmic Tail: Native Tail
Gene Symbol: CCR6
Product Line: Tango™
Reporter Gene: BLA (Beta-Lactamase)
Cell Line: U2OS
Druggable Target: GPCR
Assay Entry: Cell-based beta-arrestin recruitment
Content And Storage: Each kit contains sufficient quantities of division arrested (DA) cells and substrate to assay 1 x 384 well plate. (Other materials are required separately; please refer to the protocol).Includes:• Tango™ CCR6-bla U2OS DA cells• LiveBLAzer™-FRET B/G Loading Kit, 70 μg• Solution D• Tango™ CCR6-bla U2OS DA Assay Protocol• LiveBLAzer™-FRET B/G Loading Protocol• Certificate of AnalysisThe Tango™ CCR6-bla U2OS DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method: Fluorescence
Population Status: Single Cell Clone Origin
Quantity: 8 x 106Cells
Target Entry: CCR6
System Type: Tango™
Accession Number:
NM_004367.3
Cell State:
Division-Arrested Cells
Cytoplasmic Tail:
Native Tail
Gene Symbol:
CCR6
Product Line:
Tango™
Reporter Gene:
BLA (Beta-Lactamase)
Cell Line:
U2OS
Druggable Target:
GPCR
Assay Entry:
Cell-based beta-arrestin recruitment
Content And Storage:
Each kit contains sufficient quantities of division arrested (DA) cells and substrate to assay 1 x 384 well plate. (Other materials are required separately; please refer to the protocol).Includes:• Tango™ CCR6-bla U2OS DA cells• LiveBLAzer™-FRET B/G Loading Kit, 70 μg• Solution D• Tango™ CCR6-bla U2OS DA Assay Protocol• LiveBLAzer™-FRET B/G Loading Protocol• Certificate of AnalysisThe Tango™ CCR6-bla U2OS DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Detection Method:
Fluorescence
Population Status:
Single Cell Clone Origin
Quantity:
8 x 106Cells
Target Entry:
CCR6
System Type:
Tango™