MAGR301B

R&D Systems™ MagCellect Rat CD3+ T Cell Isolation Kit

Manufacturer: R&D Systems™

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Content And Storage

Store the unopened product at 2°C to 8°C. Do not use past expiration date.

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Description

  • The T cell receptor (TCR)/CD3 complex consists of two variable antigen-recognition receptor chains (TCR-alpha/TCR-beta or TCR-gamma/TCR-delta) that are non-covalently linked to at least four different invariant chains: CD3 gamma, CD3 delta, CD3 epsilon, and the CD3 zeta chain that exists as either a homodimer or as a heterodimer with its splice-variant the CD3 eta chain The CD3 complex functions to transduce intracellular signals during TCR antigen recognition CD3 is expressed early in thymocyte development, and on a subset of NK cells CD3 epsilon is one of at least three invariant proteins that associate with the variable antigen recognition chains of the T cell receptor and function in signal transduction

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