A2408

S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt

≥80% (HPLC), ≥80% (spectrophotometric assay)

Manufacturer: Sigma Aldrich

CAS Number: 52248-03-0

Synonym(S): AdoMet, SAM p-toluenesulfonate salt

Select a Size

Pack Size SKU Availability Price
25 MG A2408-25-MG In Stock ₹ 10,164.68
100 MG A2408-100-MG In Stock ₹ 19,701.50
500 MG A2408-500-MG In Stock ₹ 64,863.40

A2408 - 25 MG

₹ 10,164.68

In Stock

Quantity

1

Base Price: ₹ 10,164.68

GST (18%): ₹ 1,829.642

Total Price: ₹ 11,994.322

biological source

synthetic (Organic)

Quality Level

300

Assay

≥80% (HPLC)≥80% (spectrophotometric assay)

form

powder

composition

p-Toluenesulfonate content, 1.6-4.4 mol/mol

color

white to off-white

solubility

H2O: 100 mg/mL

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=C(O[H])[C@](N([H])[H])([H])C([H])([H])C([H])([H])[S@+](C([H])([H])[H])C([H])([H])[C@@]([C@](O[H])([H])[C@@]1([H])O[H])([H])O[C@]1([H])N2C3=C(N=C2[H])C(N([H])[H])=NC([H])=N3.O=S(C4=C([H])C([H])=C(C([H])([H])[H])C([H])=C4[H])([O-])=O

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Description

  • General description: S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt is used for the treatment of depression, liver cirrhosis, cholestasis and degenerative joint disease.[1]
  • Application: S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt has been used for cell proliferation assay.[2] It has also been used for methylation assay.[3][4]
  • Biochem/physiol Actions: Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.
  • Caution: This material is unstable at room temperature.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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