Dihydrofolic acid
≥90%
Manufacturer: Sigma Aldrich
CAS Number: 4033-27-6
Synonym(S): 7,8-Dihydropteroyl-L-glutamic acid, Dihydropteroyl-L-glutamic acid, FAH2
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 MG | D7006-10-MG | In Stock | ₹ 13,379.70 |
| 25 MG | D7006-25-MG | In Stock | ₹ 25,178.95 |
| 100 MG | D7006-100-MG | In Stock | ₹ 51,656.90 |
D7006 - 10 MG
In Stock
Quantity
1
Base Price: ₹ 13,379.70
GST (18%): ₹ 2,408.346
Total Price: ₹ 15,788.046
biological source
synthetic (organic)
Quality Level
200
Assay
≥90%
form
powder
color
light yellow to dark yellow-orange
storage temp.
−20°C
SMILES string
NC1=NC(=O)C2=C(NCC(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=N2)N1
InChI
1S/C19H21N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,12,21H,5-8H2,(H,24,29)(H,27,28)(H,31,32)(H4,20,22,25,26,30)/t12-/m0/s1
InChI key
OZRNSSUDZOLUSN-LBPRGKRZSA-N
Gene Information
human ... DHFRP1(573971) mouse ... Dhfr(13361)
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences Dihydrofolic acid | 4033-27-6 | MFCD00083619 | 10mg | Sigma Aldrich Fine Chemicals Biosciences | ₹ 13,206.19 | |
 | Sigma Aldrich Fine Chemicals Biosciences Dihydrofolic acid | 4033-27-6 | MFCD00083619 | 25mg | Sigma Aldrich Fine Chemicals Biosciences | ₹ 29,766.32 | |
 | eMolecules Dihydro Folic Acid | 4033-27-6 | MFCD00083619 | 100mg | eMolecules | ₹ 1,24,077.40 | |
 | Dihydrofolic acid | Sigma Aldrich | ₹ 13,379.70 - ₹ 51,656.90 | |
 | 4033-27-6 | Dihydrofolic acid | A2B Chem | ₹ 3,850.20 - ₹ 25,069.08 |
Related Products
Description
- General description: Intermediate in mammalian conversion of dietary folic acid to tetrahydrofolate by dihydrofolate reductase (DHFR). In bacteria, dihydrofolic acid is generated from 7,8-dihydropteroate by dihydrofolate synthetase.
- Application: Dihydrofolic acid has been used in diaphorase-coupled assay for dihydrofolate reductase (DHFR) activity.[1] It has also been used as a component in assay buffer to determine dihydrofolate reductase (DHFR) activity.[2]
- Biochem/physiol Actions: Folic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘one carbon′ transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidylic acid and various amino acids and for post-translational methylation (epigenetics).
- Packaging: Sealed ampule.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
biological source: synthetic (organic)
Quality Level: 200
Assay: ≥90%
form: powder
color: light yellow to dark yellow-orange
storage temp.: −20°C
SMILES string: NC1=NC(=O)C2=C(NCC(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=N2)N1
InChI: 1S/C19H21N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,12,21H,5-8H2,(H,24,29)(H,27,28)(H,31,32)(H4,20,22,25,26,30)/t12-/m0/s1
InChI key: OZRNSSUDZOLUSN-LBPRGKRZSA-N
Gene Information: human ... DHFRP1(573971) mouse ... Dhfr(13361)
biological source: __
Quality Level: 200
Assay: 99%
form: crystals
color: __
storage temp.: __
SMILES string: Oc1c(Cl)cccc1Cl
InChI: 1S/C6H4Cl2O/c7-4-2-1-3-5(8)6(4)9/h1-3,9H
InChI key: HOLHYSJJBXSLMV-UHFFFAOYSA-N
Gene Information: __
biological source: __
Quality Level: __
Assay: __
form: __
color: __
storage temp.: __
SMILES string: __
InChI: __
InChI key: __
Gene Information: __