E1257
Epidermal Growth Factor from murine submaxillary gland
lyophilized powder, BioReagent, suitable for cell culture
Manufacturer: Sigma Aldrich
CAS Number: 62229-50-9
Synonym(S): EGF, Epidermal cell growth factor
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 0.1 MG | E1257-0.1-MG | In Stock | ₹ 39,662.80 |
E1257 - 0.1 MG
In Stock
Quantity
1
Base Price: ₹ 39,662.80
GST (18%): ₹ 7,139.304
Total Price: ₹ 46,802.104
biological source
mouse submaxillary glands
Quality Level
200
product line
BioReagent
Assay
≥98% (SDS-PAGE)
form
lyophilized powder
potency
0.02-2.0 ng/mL EC50
packaging
pkg of 0.1 mg
storage condition
avoid repeated freeze/thaw cycles
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Epidermal Growth Factor from murine submaxillary gland | Sigma Aldrich | ₹ 22,754.15 - ₹ 77,431.23 | |
 | 62229-50-9 | rec EGF (mouse) H-Asn-Ser-Tyr-Pro-Gly-Cys-Pro-Ser-Ser-Tyr-Asp-Gly-Tyr-Cys-Leu-Asn-Gly-Gly-Val-Cys-Met-His-Ile-Glu-Ser-Leu-Asp-Ser-Tyr-Thr-Cys-Asn-Cys-Val-Ile-Gly-Tyr-Ser-Gly-Asp-Arg-Cys-Gln-Thr-Arg-Asp-Leu-Arg-Trp-Trp-Glu-Leu-Arg-OH (Disulfide bonds between Cys6 and Cys20/Cys14 and Cys31/Cys33 and Cys42) | A2B Chem | -- |
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Description
- General description: Epidermal growth factor (EGF) is the member of EGF-like family of growth factors, that binds to EGF receptor.[1] It is majorly expressed in kidney,[2] parotid gland and salivary gland.[3]
- Application: Epidermal Growth Factor from murine submaxillary gland has been usedin studying its effects on the development of caustic esophageal stricture in rats[4]for preparation of MCF-10A cell line[5]for the culture of primary hair follicle stem cells from arbas cashmere goat (gHFSCs) and adhesion of hair follicles (HF)[6]
- Biochem/physiol Actions: Epidermal growth factor (EGF) blocks gastric acid and pepsin secretion and increases gastrointestinal cell proliferation.[7] EGF stimulates proliferation and migration in bone marrow stromal cells (BMSC), that gives rise to osteoblasts, chondrocytes and adipocytes.[8] It functions as a strong mitogenic factor for various cultured cells. Mutations in this gene is linked to hypomagnesemia.[1] EGF plays a major role in the maintenance of hair and skin development.[9]
- Physical form: Lyophilized from 0.2 μm filtered solution in ammonium acetate buffer.
- Preparation Note: Purified by gel filtration and ion-exchange chromatography.
- Analysis Note: The biological activity is measured in a proliferation assay using BALB/MK cells.
SAFETY INFORMATION
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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biological source: mouse submaxillary glands
Quality Level: 200
product line: BioReagent
Assay: ≥98% (SDS-PAGE)
form: lyophilized powder
potency: 0.02-2.0 ng/mL EC50
packaging: pkg of 0.1 mg
storage condition: avoid repeated freeze/thaw cycles
technique(s): cell culture | mammalian: suitable
impurities: endotoxin, tested
biological source:
mouse submaxillary glands
Quality Level:
200
product line:
BioReagent
Assay:
≥98% (SDS-PAGE)
form:
lyophilized powder
potency:
0.02-2.0 ng/mL EC50
packaging:
pkg of 0.1 mg
storage condition:
avoid repeated freeze/thaw cycles
technique(s):
cell culture | mammalian: suitable
impurities:
endotoxin, tested
biological source: __
Quality Level: 100
product line: __
Assay: ≥99% (TLC)
form: powder
potency: __
packaging: __
storage condition: __
technique(s): __
impurities: __
biological source:
__
Quality Level:
100
product line:
__
Assay:
≥99% (TLC)
form:
powder
potency:
__
packaging:
__
storage condition:
__
technique(s):
__
impurities:
__
biological source: __
Quality Level: 300
product line: BioReagent
Assay: __
form: liquid
potency: __
packaging: __
storage condition: __
technique(s): cell culture | mammalian: suitable
impurities: __
biological source:
__
Quality Level:
300
product line:
BioReagent
Assay:
__
form:
liquid
potency:
__
packaging:
__
storage condition:
__
technique(s):
cell culture | mammalian: suitable
impurities:
__
biological source: __
Quality Level: 200
product line: BioXtra
Assay: ≥98% (HPLC)
form: __
potency: __
packaging: __
storage condition: __
technique(s): __
impurities: ≤0.001% Phosphorus (P)≤0.1% Insoluble matter
biological source:
__
Quality Level:
200
product line:
BioXtra
Assay:
≥98% (HPLC)
form:
__
potency:
__
packaging:
__
storage condition:
__
technique(s):
__
impurities:
≤0.001% Phosphorus (P)≤0.1% Insoluble matter