P8953
Platelet-Derived Growth Factor from porcine platelets
PDGF, lyophilized powder, suitable for cell culture
Manufacturer: Sigma Aldrich
Synonym(S): PDGF
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 μG | P8953-5-μG | In Stock | ₹ 53,183.23 |
P8953 - 5 μG
In Stock
Quantity
1
Base Price: ₹ 53,183.23
GST (18%): ₹ 9,572.981
Total Price: ₹ 62,756.211
biological source
Porcine
Quality Level
200
Assay
≥97% (SDS-PAGE and N-terminal analysis)
form
lyophilized powder
potency
39.00 ng/mL EC50
quality
endotoxin tested
mol wt
glycoprotein 38 kDa
packaging
pkg of 5 μg
storage condition
avoid repeated freeze/thaw cycles
technique(s)
cell culture | mammalian: suitable
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Description
- Application: PDGF elicits multifunctional actions with a variety of cells, including mitogenesis of mesoderm-derived cells, increased extracellular matrix synthesis, and chemotaxis and activation of neutrophils, monocytes and fibroblasts.
- Biochem/physiol Actions: The principal mitogen found in mammalian serum, released from platelets during clot formation. Elicits mitogenesis of mesoderm-derived cells, increased extracellular matrix synthesis, and chemotaxis and activation of neutrophils, monocytes and fibroblasts. Mitogenic for dermal and tendon fibroblasts, vascular smooth muscle cells, glial cells and chondrocytes. Appears to interact with transforming growth factor-β1 in accelerating wound healing. However, platelet-derived growth factor (PDGF) may also be pathogenic in arteriosclerosis and neoplasia.
- Physical form: Lyophilized from a 0.2 μm filtered solution in 40% acetonitrile and 0.1% trifluoroacetic acid, pH 2.0.
- Analysis Note: The mitogenic activity is tested in culture using Swiss 3T3 cells or NR6-3T3 fibroblasts.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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biological source: Porcine
Quality Level: 200
Assay: ≥97% (SDS-PAGE and N-terminal analysis)
form: lyophilized powder
potency: 39.00 ng/mL EC50
quality: endotoxin tested
mol wt: glycoprotein 38 kDa
packaging: pkg of 5 μg
storage condition: avoid repeated freeze/thaw cycles
technique(s): cell culture | mammalian: suitable
biological source:
Porcine
Quality Level:
200
Assay:
≥97% (SDS-PAGE and N-terminal analysis)
form:
lyophilized powder
potency:
39.00 ng/mL EC50
quality:
endotoxin tested
mol wt:
glycoprotein 38 kDa
packaging:
pkg of 5 μg
storage condition:
avoid repeated freeze/thaw cycles
technique(s):
cell culture | mammalian: suitable
biological source: __
Quality Level: __
Assay: __
form: __
potency: __
quality: __
mol wt: __
packaging: case of 30 ea (internal packs of 10)
storage condition: __
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Assay:
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form:
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mol wt:
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packaging:
case of 30 ea (internal packs of 10)
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biological source: rabbit
Quality Level: 200
Assay: __
form: lyophilized powder
potency: __
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technique(s): flow cytometry: 10 μg/test using Jurkat T-cells
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rabbit
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200
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lyophilized powder
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flow cytometry: 10 μg/test using Jurkat T-cells
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