I8523
Interleukin-12 from mouse
≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture
Manufacturer: Sigma Aldrich
Synonym(S): IL-12
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 μG | I8523-10-μG | In Stock | ₹ 57,930.90 |
I8523 - 10 μG
In Stock
Quantity
1
Base Price: ₹ 57,930.90
GST (18%): ₹ 10,427.562
Total Price: ₹ 68,358.462
biological source
mouse
Quality Level
100
recombinant
expressed in baculovirus infected Sf21 cells
Assay
≥97% (SDS-PAGE)
form
lyophilized powder
potency
0.01-.1 ng/mL ED50
mol wt
glycoprotein 70 kDa
packaging
pkg of 10 μg
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
Related Products
Description
- Application: Interleukin-12 (IL-12) from mouse has been used to study the effect of IL-12 on Th1 (type 1 T helper) immunity in Mongolian gerbils (Meriones unguiculatus) infected with Sporothrix schenckii.[1] It has been used as a standard in ELISA (enzyme-linked immunosorbent assay) cytokine assay.[2]
- Biochem/physiol Actions: Interleukin-12 (IL-12) was identified as a factor secreted by human Epstein-Barr (EBV)-transformed B cell lines. IL-12, or Natural Killer Cell Stimulatory Factor (NKSF), is a 75 kDa disulfide-linked heterodimer of a 35 kDa subunit and 40 kDa subunit. IL-12 is produced predominantly by monocytes and NK cells and induces T cells and NK cells to produce IFN-γ. Human IL-12 is not active on mouse cells, but murine IL-12 is active on both murine and human lymphocytes. The biological activity of recombinant human IL-12 was measured by its ability to stimulate the proliferation of PHA-activated human T lymphoblasts. IL-12 has anti-angiogenic properties.
- Physical form: Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.5 mg bovine serum albumin.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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biological source: mouse
Quality Level: 100
recombinant: expressed in baculovirus infected Sf21 cells
Assay: ≥97% (SDS-PAGE)
form: lyophilized powder
potency: 0.01-.1 ng/mL ED50
mol wt: glycoprotein 70 kDa
packaging: pkg of 10 μg
technique(s): cell culture | mammalian: suitable
impurities: endotoxin, tested
biological source:
mouse
Quality Level:
100
recombinant:
expressed in baculovirus infected Sf21 cells
Assay:
≥97% (SDS-PAGE)
form:
lyophilized powder
potency:
0.01-.1 ng/mL ED50
mol wt:
glycoprotein 70 kDa
packaging:
pkg of 10 μg
technique(s):
cell culture | mammalian: suitable
impurities:
endotoxin, tested
biological source: rabbit
Quality Level: 300
recombinant: __
Assay: __
form: __
potency: __
mol wt: __
packaging: __
technique(s): indirect ELISA: 1:60,000quantitative precipitin assay: 2.5 mg/mL
impurities: __
biological source:
rabbit
Quality Level:
300
recombinant:
__
Assay:
__
form:
__
potency:
__
mol wt:
__
packaging:
__
technique(s):
indirect ELISA: 1:60,000quantitative precipitin assay: 2.5 mg/mL
impurities:
__
biological source: human
Quality Level: 100
recombinant: expressed in E. coli
Assay: >97% (SDS-PAGE)
form: lyophilized powder
potency: 0.2-4.0 ng/mL EC50
mol wt: antigen predicted mol wt ~12.5 kDa
packaging: pkg of 5 μg
technique(s): cell culture | mammalian: suitable
impurities: endotoxin, tested
biological source:
human
Quality Level:
100
recombinant:
expressed in E. coli
Assay:
>97% (SDS-PAGE)
form:
lyophilized powder
potency:
0.2-4.0 ng/mL EC50
mol wt:
antigen predicted mol wt ~12.5 kDa
packaging:
pkg of 5 μg
technique(s):
cell culture | mammalian: suitable
impurities:
endotoxin, tested
biological source: __
Quality Level: 200
recombinant: __
Assay: ≥99%
form: powder
potency: __
mol wt: __
packaging: __
technique(s): __
impurities: __
biological source:
__
Quality Level:
200
recombinant:
__
Assay:
≥99%
form:
powder
potency:
__
mol wt:
__
packaging:
__
technique(s):
__
impurities:
__