N1905

Neurotrophin-3 human

recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture, >97% (SDS-PAGE)

Manufacturer: Sigma Aldrich

Synonym(S): HDNF, NTF3, NT-3

Select a Size

Pack Size SKU Availability Price
5 μG N1905-5-μG In Stock ₹ 40,095.80

N1905 - 5 μG

₹ 40,095.80

In Stock

Quantity

1

Base Price: ₹ 40,095.80

GST (18%): ₹ 7,217.244

Total Price: ₹ 47,313.044

biological source

human

Quality Level

200

recombinant

expressed in baculovirus infected Sf21 cells

Assay

>97% (SDS-PAGE)

form

lyophilized powder

potency

1-40 ng/mL EC50

packaging

pkg of 5 μg

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

P20783

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Description

  • General description: NTF3 (neurotrophin 3) is a neurotrophic factor belonging to the NGF (nerve growth factor) family.[1] This protein is made up of 257 amino acids, with a prepro region of 138 amino acids and the mature sequence of 119 residues.[2]
  • Application: Neurotrophin-3 human has been used in the magnetic sorting of oligodendrocyte progenitor cells.[3]
  • Biochem/physiol Actions: Neurotrophin-3 (13.6 kDa or 27.2 kDa dimer) is a member of the neurotrophin family. It has identical amino acid sequence in human, mouse, and pig with full cross-reactivities. NT-3 is important in development and maintenance of neuronal populations and promotes differentiation of neural crest derived sensory and sympathetic neurons. It is critical for proprioceptive 1a afferent neurons, which relay information from peripheral muscle spindles to motoneurons, sending projections to spinocerebellar neurons. NT-3 is also critical in the superior cervical and nodose ganglia.
  • Physical form: Lyophilized from a 0.2 m filtered solution in phosphate buffered saline (PBS) containing 50 μg of bovine serum albumin (BSA) per 1 μg of cytokine.
  • Analysis Note: The biological activity is measured in a cell proliferation assay using a TrkB-transfected cell line BaF-TrkB-BD.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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biological source:
human

Quality Level:
200

recombinant:
expressed in baculovirus infected Sf21 cells

Assay:
>97% (SDS-PAGE)

form:
lyophilized powder

potency:
1-40 ng/mL EC50

packaging:
pkg of 5 μg

technique(s):
cell culture | mammalian: suitable

impurities:
endotoxin, tested

UniProt accession no.:
P20783

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