O4264
Human Osteopontin
recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture
Manufacturer: Sigma Aldrich
Synonym(S): Bone Sialoprotein-1, Early T Lymphocyte Activation Protein-1 (ETA-1), OPN, Secreted Phosphoprotein 1 (Spp1)
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 μG | O4264-50-μG | In Stock | ₹ 62,512.80 |
O4264 - 50 μG
In Stock
Quantity
1
Base Price: ₹ 62,512.80
GST (18%): ₹ 11,252.304
Total Price: ₹ 73,765.104
product name
Osteopontin human, recombinant, expressed in NSO cells, ≥95% (SDS-PAGE), lyophilized powder, suitable for cell culture
biological source
human
Quality Level
100
recombinant
expressed in NSO cells
sterility
sterile
Assay
≥95% (SDS-PAGE)
form
lyophilized powder
mol wt
60-65 kDa by SDS-PAGE (reducing)
packaging
pkg of 50 μg
technique(s)
cell culture | mammalian: suitable
Related Products
Description
- General description: Secreted phosphoprotein 1 (SPP1) or osteopontin is a secreted cytokine. This phosphorylated acidic glycoprotein is expressed in various cells and tissues. It is synthesized by osteoblasts. The gene encoding SPP1 is localized on human chromosome 4q22.1.[1][2][3]
- Application: Anti-Osteopontin antibody produced in rabbit has been used for ELISA.[4]
- Biochem/physiol Actions: A secreted, highly acidic, calcium binding, phosphorylated glycoprotein that is chemotactic for macrophages, smooth muscle cells, endothelial cells, and glial cells. In activated macrophages, OPN inhibits nitric oxide production and cytotoxicity. Human, mouse, rat, pig, and bovine OPN share 40% amino acid sequence identity. Secreted phosphoprotein 1 (SPP1) or osteopontin modulates inflammatory responses and glucose metabolism. It is a chemotactic factor and has a role in immune cell recruitment. The protein is also associated with cell growth, migration and differentiation. SPP1 attaches osteoclasts to the bone matrix. It is also involved in atherosclerotic process and bone mineralization.[5][6] It is a marker of many cancers.[7][1][2]
- Physical form: Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 2.5 mg bovine serum albumin.
- Analysis Note: The biological activity is measured by its ability to mediate 293 cell adhesion.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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product name: Osteopontin human, recombinant, expressed in NSO cells, ≥95% (SDS-PAGE), lyophilized powder, suitable for cell culture
biological source: human
Quality Level: 100
recombinant: expressed in NSO cells
sterility: sterile
Assay: ≥95% (SDS-PAGE)
form: lyophilized powder
mol wt: 60-65 kDa by SDS-PAGE (reducing)
packaging: pkg of 50 μg
technique(s): cell culture | mammalian: suitable
product name:
Osteopontin human, recombinant, expressed in NSO cells, ≥95% (SDS-PAGE), lyophilized powder, suitable for cell culture
biological source:
human
Quality Level:
100
recombinant:
expressed in NSO cells
sterility:
sterile
Assay:
≥95% (SDS-PAGE)
form:
lyophilized powder
mol wt:
60-65 kDa by SDS-PAGE (reducing)
packaging:
pkg of 50 μg
technique(s):
cell culture | mammalian: suitable
product name: L-Ornithine monohydrochloride, BioXtra, ≥99%
biological source: __
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sterility: __
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form: powder
mol wt: __
packaging: __
technique(s): __
product name:
L-Ornithine monohydrochloride, BioXtra, ≥99%
biological source:
__
Quality Level:
200
recombinant:
__
sterility:
__
Assay:
≥99%
form:
powder
mol wt:
__
packaging:
__
technique(s):
__
product name: __
biological source: synthetic (organic)
Quality Level: 200
recombinant: __
sterility: __
Assay: __
form: solution
mol wt: __
packaging: __
technique(s): __
product name:
__
biological source:
synthetic (organic)
Quality Level:
200
recombinant:
__
sterility:
__
Assay:
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form:
solution
mol wt:
__
packaging:
__
technique(s):
__
product name: __
biological source: __
Quality Level: 200
recombinant: __
sterility: __
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technique(s): HPLC: suitablegas chromatography (GC): suitable
product name:
__
biological source:
__
Quality Level:
200
recombinant:
__
sterility:
__
Assay:
__
form:
__
mol wt:
__
packaging:
__
technique(s):
HPLC: suitablegas chromatography (GC): suitable