O4876

Oligomycin

from Streptomyces diastatochromogenes, ≥90% total oligomycins basis (HPLC), powder, antibiotic

Manufacturer: Sigma Aldrich

CAS Number: 1404-19-9

Select a Size

Pack Size SKU Availability Price
5 MG O4876-5-MG In Stock ₹ 10,045.60
25 MG O4876-25-MG In Stock ₹ 44,577.35
100 MG O4876-100-MG In Stock ₹ 1,05,392.20
250 MG O4876-250-MG In Stock ₹ 1,92,609.23

O4876 - 5 MG

₹ 10,045.60

In Stock

Quantity

1

Base Price: ₹ 10,045.60

GST (18%): ₹ 1,808.208

Total Price: ₹ 11,853.808

product name

Oligomycin from Streptomyces diastatochromogenes, ≥90% total oligomycins basis (HPLC)

Quality Level

200

Assay

≥90% total oligomycins basis (HPLC)

form

powder

antibiotic activity spectrum

fungi

Mode of action

enzyme | inhibits

storage temp.

−20°C

InChI

1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15-,21-18+

InChI key

MNULEGDCPYONBU-ZUSSGZTJSA-N

Other Options

Image Product Name Manufacturer Price Range
49-545-510MG
MilliporeSigma™ Calbiochem™ Oligomycin
MilliporeSigma™ --
50-175-4720
Sigma Aldrich Fine Chemicals Biosciences Oligomycin from Streptomyces diastatochromogenes >=90% total oligomycins basis (HPLC) | 1404-19-9 | MFCD01779388 | 250MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 2,49,193.50
O4876
Oligomycin
Sigma Aldrich ₹ 10,045.60 - ₹ 1,92,609.23
AA62479
1404-19-9 | Oligomycin
A2B Chem ₹ 2,823.48 - ₹ 42,352.20

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Description

  • General description: Chemical structure: macrolide
  • Application: Oligomycin from Streptomyces diastatochromogenes is used:in the inhibition of mitochondrial ATP production Leigh syndrome (LS) cells.[1]in ATP-linked respiration and maximal capacity respiration assay in astrocytes.[2]in measurement of oxygen consumption rate (OCR) and extracellular acidification rates in breast cancer cell lines.[3]
  • Biochem/physiol Actions: Oligomycin belongs to the macrolide group of antibiotics.[4] It inhibits mitochondrial ATP-synthase enzyme and phosphoryl group transfer.[5] Oligomycin interacts with ATP synthase subunit-c in the Fo portion and impairs proton transport.[6]
  • Other Notes: A mixture of oligomycins A, B, and C.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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product name:
Oligomycin from Streptomyces diastatochromogenes, ≥90% total oligomycins basis (HPLC)

Quality Level:
200

Assay:
≥90% total oligomycins basis (HPLC)

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powder

antibiotic activity spectrum:
fungi

Mode of action:
enzyme | inhibits

storage temp.:
−20°C

InChI:
1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15-,21-18+

InChI key:
MNULEGDCPYONBU-ZUSSGZTJSA-N

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1S/C22H31NO3.ClH/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20;/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3;1H

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SWIJYDAEGSIQPZ-UHFFFAOYSA-N

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1S/C28H58/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-28H2,1-2H3

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ZYURHZPYMFLWSH-UHFFFAOYSA-N