P7130
Puromycin aminonucleoside
Manufacturer: Sigma Aldrich
CAS Number: 58-60-6
Synonym(S): 3′-Amino-3′-deoxy-N6,N6-dimethyladenosine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | P7130-100-MG | In Stock | ₹ 36,447.78 |
| 500 MG | P7130-500-MG | In Stock | ₹ 1,38,787.33 |
| 1 G | P7130-1-G | In Stock | ₹ 2,60,720.13 |
P7130 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 36,447.78
GST (18%): ₹ 6,560.60
Total Price: ₹ 43,008.38
form
powder
Quality Level
300
solubility
H2O: soluble 50 mg/mL
antibiotic activity spectrum
Gram-positive bacterianeoplasticsparasites
Mode of action
protein synthesis | interferes
storage temp.
2-8°C
SMILES string
CN(C)c1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@H](N)[C@@H]3O
InChI
1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3/t6-,7+,9+,12-/m1/s1
InChI key
RYSMHWILUNYBFW-VENHTOENSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Puromycin aminonucleoside Ready Made Solution | Sigma Aldrich | ₹ 16,486.48 | |
 | Puromycin aminonucleoside | Sigma Aldrich | ₹ 36,447.78 - ₹ 2,60,720.13 | |
| | Puromycin aminonucleoside Ready Made Solution | Sigma Aldrich | ₹ 16,486.48 | |
 | Puromycin aminonucleoside | ChemScene | ₹ 16,598.64 - ₹ 82,308.72 | |
 | 58-60-6 | PUROMYCIN AMINONUCLEOSIDE | A2B Chem | ₹ 4,791.36 - ₹ 32,085.00 |
Related Products
Description
- General description: Puromycin aminonucleoside is the aminonucleoside portion of the antibiotic puromycin. It is useful in nephrology research, like studies of focal and segmental glomerulosclerosis and in the induction of nephrosis in rats. The excretion of sodium and nitrite (NOx) metabolites in rats with puromycin aminonucleoside-induced nephrotic syndrome are studied. Puromycin aminonucleoside-induced nephrosis in rats has been studied with respect to the production of reactive oxygen species during the acute phase. Puromycin aminonucleoside is used to probe endothelial glycosaminoglycan synthesis in cultured glomerular endothelial cells and their relation to cell permeability.
- Application: Puromycin aminonucleoside has been used: as a selection marker for the infected cells for the transfection of lentivirusas a component of fresh medium for transfection and infection assaysto subcutaneously induce puromycin aminonucleoside nephrosis to investigate the mRNA and protein levels of nephrin and podocin before the onset of proteinuria
- Biochem/physiol Actions: Puromycin aminonucleoside is used to study human glomerular disease by inducing damage of murine glomerular podocytes and is used to study glomerular function and morphology.
- Other Notes: Keep container tightly closed in a dry and well-ventilated place.
SAFETY INFORMATION
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form: powder
Quality Level: 300
solubility: H2O: soluble 50 mg/mL
antibiotic activity spectrum: Gram-positive bacterianeoplasticsparasites
Mode of action: protein synthesis | interferes
storage temp.: 2-8°C
SMILES string: CN(C)c1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@H](N)[C@@H]3O
InChI: 1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3/t6-,7+,9+,12-/m1/s1
InChI key: RYSMHWILUNYBFW-VENHTOENSA-N
form:
powder
Quality Level:
300
solubility:
H2O: soluble 50 mg/mL
antibiotic activity spectrum:
Gram-positive bacterianeoplasticsparasites
Mode of action:
protein synthesis | interferes
storage temp.:
2-8°C
SMILES string:
CN(C)c1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@H](N)[C@@H]3O
InChI:
1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3/t6-,7+,9+,12-/m1/s1
InChI key:
RYSMHWILUNYBFW-VENHTOENSA-N
form: powder
Quality Level: 200
solubility: __
antibiotic activity spectrum: mycobacteria
Mode of action: cell membrane | interferes
storage temp.: __
SMILES string: NC(=O)c1cnccn1
InChI: 1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)
InChI key: IPEHBUMCGVEMRF-UHFFFAOYSA-N
form:
powder
Quality Level:
200
solubility:
__
antibiotic activity spectrum:
mycobacteria
Mode of action:
cell membrane | interferes
storage temp.:
__
SMILES string:
NC(=O)c1cnccn1
InChI:
1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)
InChI key:
IPEHBUMCGVEMRF-UHFFFAOYSA-N
form: powder
Quality Level: 200
solubility: __
antibiotic activity spectrum: mycobacteria
Mode of action: cell membrane | interferes
storage temp.: __
SMILES string: NC(=O)c1cnccn1
InChI: 1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)
InChI key: IPEHBUMCGVEMRF-UHFFFAOYSA-N
form:
powder
Quality Level:
200
solubility:
__
antibiotic activity spectrum:
mycobacteria
Mode of action:
cell membrane | interferes
storage temp.:
__
SMILES string:
NC(=O)c1cnccn1
InChI:
1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)
InChI key:
IPEHBUMCGVEMRF-UHFFFAOYSA-N
form: solution
Quality Level: 200
solubility: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: 2-8°C
SMILES string: __
InChI: __
InChI key: __
form:
solution
Quality Level:
200
solubility:
__
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
2-8°C
SMILES string:
__
InChI:
__
InChI key:
__