SBR00017
Puromycin aminonucleoside Ready Made Solution
10 mg/mL in water
Manufacturer: Sigma Aldrich
CAS Number: 58-60-6
Synonym(S): 3′-Amino-3′-deoxy-N6,N6-dimethyladenosine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 ML | SBR00017-1-ML | In Stock | ₹ 16,486.48 |
SBR00017 - 1 ML
In Stock
Quantity
1
Base Price: ₹ 16,486.48
GST (18%): ₹ 2,967.566
Total Price: ₹ 19,454.046
Assay
≥98%
Quality Level
200
form
liquid
concentration
10 mg/mL in water
antibiotic activity spectrum
Gram-positive bacterianeoplasticsparasites
Mode of action
protein synthesis | interferes
storage temp.
2-8°C
SMILES string
N[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(N(C)C)=NC=N3)O[C@@H]1CO
InChI
1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3
InChI key
RYSMHWILUNYBFW-UHFFFAOYSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Puromycin aminonucleoside | Sigma Aldrich | ₹ 36,447.78 - ₹ 2,60,720.13 | |
| | Puromycin aminonucleoside | Sigma Aldrich | ₹ 36,447.78 - ₹ 2,60,720.13 | |
 | Puromycin aminonucleoside Ready Made Solution | Sigma Aldrich | ₹ 16,486.48 | |
 | Puromycin aminonucleoside | ChemScene | ₹ 16,598.64 - ₹ 82,308.72 | |
 | 58-60-6 | PUROMYCIN AMINONUCLEOSIDE | A2B Chem | ₹ 4,791.36 - ₹ 32,085.00 |
Related Products
Description
- Biochem/physiol Actions: Puromycin aminonucleoside is an aminonucleoside derivative of the known antibiotic puromycin. Puromycin aminonucleoside has been used in nephrology research, studying focal and segmental glomerulosclerosis, and in the induction of nephrosis in rats.[1][2][3] Rats with puromycin aminonucleoside-induced nephrotic syndrome were used to study the excretion of sodium and NOx metabolites.[4]Puromycin aminonucleoside has also been used to probe endothelial glycosaminoglycan synthesis in cultured glomerular endothelial cells and their relation to cell permeability.[5] A puromycin aminonucleoside nephrosis model of rat glomerular disease was also used to study the role of the neuron-specific ubiquitin C-terminal hydrolase protein gene product 9.5 (PGP 9.5).[6]
- Preparation Note: Puromycin aminonucleoside solution is provided at 10 mg/mL in water and could be further diluted in aqueous buffers to a working concentration of 10 μg/mL (1:1000).
SAFETY INFORMATION
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
Assay: ≥98%
Quality Level: 200
form: liquid
concentration: 10 mg/mL in water
antibiotic activity spectrum: Gram-positive bacterianeoplasticsparasites
Mode of action: protein synthesis | interferes
storage temp.: 2-8°C
SMILES string: N[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(N(C)C)=NC=N3)O[C@@H]1CO
InChI: 1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3
InChI key: RYSMHWILUNYBFW-UHFFFAOYSA-N
Assay:
≥98%
Quality Level:
200
form:
liquid
concentration:
10 mg/mL in water
antibiotic activity spectrum:
Gram-positive bacterianeoplasticsparasites
Mode of action:
protein synthesis | interferes
storage temp.:
2-8°C
SMILES string:
N[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(N(C)C)=NC=N3)O[C@@H]1CO
InChI:
1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3
InChI key:
RYSMHWILUNYBFW-UHFFFAOYSA-N
Assay: __
Quality Level: __
form: solution
concentration: (20,000-40,000 IU/mL in 0.02N HCl)
antibiotic activity spectrum: Gram-positive bacteria
Mode of action: cell membrane | interferes
storage temp.: −20°C
SMILES string: O=C(N[C@H](C(NC(C(N[C@@H](CCCCN)C(O)=O)=O)=C)=O)C(C)C)[C@@H](NC([C@H]([C@@H](C)CC)NC([C@@H](NC([C@@H](NC([C@H](CC1=CN=CN1)NC2=O)=O)CS[C@H]([C@@H]3C(N[C@H]2CS[C@H]([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CNC4=O)=
InChI: 1S/C143H230N42O37S7/c1-24-69(11)105(148)135(213)162-82(27-4)118(196)174-94-58-225-59-95(175-123(201)89(48-67(7)8)169-115(193)74(16)158-138(216)107(70(12)25-2)180-132(94)210)133(211)184-112-79(21)229-61-96(160-104(190)56-152-134(212)100-38-34-44-185(100)142(112)220)128(206)164-84(36-29-32-42-145)120(198)182-109-76(18)226-60-97(161-103(189)55-151-117(195)85(39-45-223-22)165-122(200)88(47-66(5)6)168-113(191)72(14)156-102(188)54-153-136(109)214)129(207)171-92(51-101(147)187)125(203)166-86(40-46-224-23)119(197)163-83(35-28-31-41-144)121(199)183-110-77(19)228-63-99-130(208)170-90(49-80-52-149-64-154-80)124(202)176-98(62-227-78(20)111(141(219)177-99)181-116(194)75(17)159-140(110)218)131(209)173-93(57-186)127(205)179-108(71(13)26-3)139(217)172-91(50-81-53-150-65-155-81)126(204)178-106(68(9)10)137(215)157-73(15)114(192)167-87(143(221)222)37-30-33-43-146/h27,52-53,64-72,75-79,83-100,105-112,186H,15-16,24-26,28-51,54-63,144-146,148H2,1-14,17-23H3,(H2,147,187)(H,149,154)(H,150,155)(H,151,195)(H,152,212)(H,153,214)(H,156,188)(H,157,215)(H,158,216)(H,159,218)(H,160,190)(H,161,189)(H,162,213)(H,163,197)(H,164,206)(H,165,200)(H,166,203)(H,167,192)(H,168,191)(H,169,193)(H,170,208)(H,171,207)(H,172,217)(H,173,209)(H,174,196)(H,175,201)(H,176,202)(H,177,219)(H,178,204)(H,179,205)(H,180,210)(H,181,194)(H,182,198)(H,183,199)(H,184,211)(H,221,222)/b82-27-
InChI key: __
Assay:
__
Quality Level:
__
form:
solution
concentration:
(20,000-40,000 IU/mL in 0.02N HCl)
antibiotic activity spectrum:
Gram-positive bacteria
Mode of action:
cell membrane | interferes
storage temp.:
−20°C
SMILES string:
O=C(N[C@H](C(NC(C(N[C@@H](CCCCN)C(O)=O)=O)=C)=O)C(C)C)[C@@H](NC([C@H]([C@@H](C)CC)NC([C@@H](NC([C@@H](NC([C@H](CC1=CN=CN1)NC2=O)=O)CS[C@H]([C@@H]3C(N[C@H]2CS[C@H]([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CNC4=O)=
InChI:
1S/C143H230N42O37S7/c1-24-69(11)105(148)135(213)162-82(27-4)118(196)174-94-58-225-59-95(175-123(201)89(48-67(7)8)169-115(193)74(16)158-138(216)107(70(12)25-2)180-132(94)210)133(211)184-112-79(21)229-61-96(160-104(190)56-152-134(212)100-38-34-44-185(100)142(112)220)128(206)164-84(36-29-32-42-145)120(198)182-109-76(18)226-60-97(161-103(189)55-151-117(195)85(39-45-223-22)165-122(200)88(47-66(5)6)168-113(191)72(14)156-102(188)54-153-136(109)214)129(207)171-92(51-101(147)187)125(203)166-86(40-46-224-23)119(197)163-83(35-28-31-41-144)121(199)183-110-77(19)228-63-99-130(208)170-90(49-80-52-149-64-154-80)124(202)176-98(62-227-78(20)111(141(219)177-99)181-116(194)75(17)159-140(110)218)131(209)173-93(57-186)127(205)179-108(71(13)26-3)139(217)172-91(50-81-53-150-65-155-81)126(204)178-106(68(9)10)137(215)157-73(15)114(192)167-87(143(221)222)37-30-33-43-146/h27,52-53,64-72,75-79,83-100,105-112,186H,15-16,24-26,28-51,54-63,144-146,148H2,1-14,17-23H3,(H2,147,187)(H,149,154)(H,150,155)(H,151,195)(H,152,212)(H,153,214)(H,156,188)(H,157,215)(H,158,216)(H,159,218)(H,160,190)(H,161,189)(H,162,213)(H,163,197)(H,164,206)(H,165,200)(H,166,203)(H,167,192)(H,168,191)(H,169,193)(H,170,208)(H,171,207)(H,172,217)(H,173,209)(H,174,196)(H,175,201)(H,176,202)(H,177,219)(H,178,204)(H,179,205)(H,180,210)(H,181,194)(H,182,198)(H,183,199)(H,184,211)(H,221,222)/b82-27-
InChI key:
__
Assay: __
Quality Level: __
form: solution
concentration: (20,000-40,000 IU/mL in 0.02N HCl)
antibiotic activity spectrum: Gram-positive bacteria
Mode of action: cell membrane | interferes
storage temp.: −20°C
SMILES string: O=C(N[C@H](C(NC(C(N[C@@H](CCCCN)C(O)=O)=O)=C)=O)C(C)C)[C@@H](NC([C@H]([C@@H](C)CC)NC([C@@H](NC([C@@H](NC([C@H](CC1=CN=CN1)NC2=O)=O)CS[C@H]([C@@H]3C(N[C@H]2CS[C@H]([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CNC4=O)=
InChI: 1S/C143H230N42O37S7/c1-24-69(11)105(148)135(213)162-82(27-4)118(196)174-94-58-225-59-95(175-123(201)89(48-67(7)8)169-115(193)74(16)158-138(216)107(70(12)25-2)180-132(94)210)133(211)184-112-79(21)229-61-96(160-104(190)56-152-134(212)100-38-34-44-185(100)142(112)220)128(206)164-84(36-29-32-42-145)120(198)182-109-76(18)226-60-97(161-103(189)55-151-117(195)85(39-45-223-22)165-122(200)88(47-66(5)6)168-113(191)72(14)156-102(188)54-153-136(109)214)129(207)171-92(51-101(147)187)125(203)166-86(40-46-224-23)119(197)163-83(35-28-31-41-144)121(199)183-110-77(19)228-63-99-130(208)170-90(49-80-52-149-64-154-80)124(202)176-98(62-227-78(20)111(141(219)177-99)181-116(194)75(17)159-140(110)218)131(209)173-93(57-186)127(205)179-108(71(13)26-3)139(217)172-91(50-81-53-150-65-155-81)126(204)178-106(68(9)10)137(215)157-73(15)114(192)167-87(143(221)222)37-30-33-43-146/h27,52-53,64-72,75-79,83-100,105-112,186H,15-16,24-26,28-51,54-63,144-146,148H2,1-14,17-23H3,(H2,147,187)(H,149,154)(H,150,155)(H,151,195)(H,152,212)(H,153,214)(H,156,188)(H,157,215)(H,158,216)(H,159,218)(H,160,190)(H,161,189)(H,162,213)(H,163,197)(H,164,206)(H,165,200)(H,166,203)(H,167,192)(H,168,191)(H,169,193)(H,170,208)(H,171,207)(H,172,217)(H,173,209)(H,174,196)(H,175,201)(H,176,202)(H,177,219)(H,178,204)(H,179,205)(H,180,210)(H,181,194)(H,182,198)(H,183,199)(H,184,211)(H,221,222)/b82-27-
InChI key: __
Assay:
__
Quality Level:
__
form:
solution
concentration:
(20,000-40,000 IU/mL in 0.02N HCl)
antibiotic activity spectrum:
Gram-positive bacteria
Mode of action:
cell membrane | interferes
storage temp.:
−20°C
SMILES string:
O=C(N[C@H](C(NC(C(N[C@@H](CCCCN)C(O)=O)=O)=C)=O)C(C)C)[C@@H](NC([C@H]([C@@H](C)CC)NC([C@@H](NC([C@@H](NC([C@H](CC1=CN=CN1)NC2=O)=O)CS[C@H]([C@@H]3C(N[C@H]2CS[C@H]([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CNC4=O)=
InChI:
1S/C143H230N42O37S7/c1-24-69(11)105(148)135(213)162-82(27-4)118(196)174-94-58-225-59-95(175-123(201)89(48-67(7)8)169-115(193)74(16)158-138(216)107(70(12)25-2)180-132(94)210)133(211)184-112-79(21)229-61-96(160-104(190)56-152-134(212)100-38-34-44-185(100)142(112)220)128(206)164-84(36-29-32-42-145)120(198)182-109-76(18)226-60-97(161-103(189)55-151-117(195)85(39-45-223-22)165-122(200)88(47-66(5)6)168-113(191)72(14)156-102(188)54-153-136(109)214)129(207)171-92(51-101(147)187)125(203)166-86(40-46-224-23)119(197)163-83(35-28-31-41-144)121(199)183-110-77(19)228-63-99-130(208)170-90(49-80-52-149-64-154-80)124(202)176-98(62-227-78(20)111(141(219)177-99)181-116(194)75(17)159-140(110)218)131(209)173-93(57-186)127(205)179-108(71(13)26-3)139(217)172-91(50-81-53-150-65-155-81)126(204)178-106(68(9)10)137(215)157-73(15)114(192)167-87(143(221)222)37-30-33-43-146/h27,52-53,64-72,75-79,83-100,105-112,186H,15-16,24-26,28-51,54-63,144-146,148H2,1-14,17-23H3,(H2,147,187)(H,149,154)(H,150,155)(H,151,195)(H,152,212)(H,153,214)(H,156,188)(H,157,215)(H,158,216)(H,159,218)(H,160,190)(H,161,189)(H,162,213)(H,163,197)(H,164,206)(H,165,200)(H,166,203)(H,167,192)(H,168,191)(H,169,193)(H,170,208)(H,171,207)(H,172,217)(H,173,209)(H,174,196)(H,175,201)(H,176,202)(H,177,219)(H,178,204)(H,179,205)(H,180,210)(H,181,194)(H,182,198)(H,183,199)(H,184,211)(H,221,222)/b82-27-
InChI key:
__
Assay: ≥98% (HPLC)
Quality Level: 200
form: liquid
concentration: 10 mg/mL (20 mM HEPES)
antibiotic activity spectrum: fungi
Mode of action: protein synthesis | interferes
storage temp.: −20°C
SMILES string: CN(CCC(CC(=O)NC1C=CC(OC1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl
InChI: __
InChI key: __
Assay:
≥98% (HPLC)
Quality Level:
200
form:
liquid
concentration:
10 mg/mL (20 mM HEPES)
antibiotic activity spectrum:
fungi
Mode of action:
protein synthesis | interferes
storage temp.:
−20°C
SMILES string:
CN(CCC(CC(=O)NC1C=CC(OC1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl
InChI:
__
InChI key:
__