SRP3049
GDF-2 human
recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture
Manufacturer: Sigma Aldrich
Synonym(S): BMP-9, Growth/Differentiation Factor-2
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 μG | SRP3049-10-μG | In Stock | ₹ 34,943.10 |
SRP3049 - 10 μG
In Stock
Quantity
1
Base Price: ₹ 34,943.10
GST (18%): ₹ 6,289.758
Total Price: ₹ 41,232.858
biological source
human
recombinant
expressed in CHO cells
Assay
≥95% (HPLC)≥95% (SDS-PAGE)
form
lyophilized
potency
0.5-1.9 ng/mL
mol wt
24.1 kDa
packaging
pkg of 10 μg
technique(s)
cell culture | mammalian: suitable
impurities
<0.1 EU/μg endotoxin, tested
color
white to off-white
Description
- General description: GDF-2 belongs to the TGF-β cytokine family whose members play an important role during prenatal development and postnatal growth, remodeling and maintenance of a variety of tissues and organs. GDF-2 is expressed mainly in nonparenchymal cells of the liver, but is also found in other various cells and tissues. GDF-2 can signal through the ALK1 receptor and has been implicated in a number of physiologic events. These include regulation of the hepatic reticuloendothelial system, glucose homeostasis, and iron homeostasis, as well as the inhibition of angiogenesis. Recombinant human GDF-2 is a 24.1 kDa disulfide linked homodimeric protein consisting of two 110 amino acid polypeptide chains.
- Biochem/physiol Actions: GDF-2 belongs to the TGF-β cytokine family whose members play an important role during prenatal development and postnatal growth, remodeling and maintenance of a variety of tissues and organs. Recombinant human GDF-2 is a 24.1 kDa disulfide linked homodimeric protein consisting of two 110 amino acid polypeptide chains.
- Sequence: SAGAGSHCQK TSLRVNFEDI GWDSWIIAPKE YEAYECKGGC FFPLADDVTPTK HAIVQTLVHL KFPTKVGKAC CVPTKLSPIS VLYKDDMGVP TLKYHYEGMS VAECGCR
- Physical form: Lyophilized with no additives.
- Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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biological source: human
recombinant: expressed in CHO cells
Assay: ≥95% (HPLC)≥95% (SDS-PAGE)
form: lyophilized
potency: 0.5-1.9 ng/mL
mol wt: 24.1 kDa
packaging: pkg of 10 μg
technique(s): cell culture | mammalian: suitable
impurities: <0.1 EU/μg endotoxin, tested
color: white to off-white
biological source:
human
recombinant:
expressed in CHO cells
Assay:
≥95% (HPLC)≥95% (SDS-PAGE)
form:
lyophilized
potency:
0.5-1.9 ng/mL
mol wt:
24.1 kDa
packaging:
pkg of 10 μg
technique(s):
cell culture | mammalian: suitable
impurities:
<0.1 EU/μg endotoxin, tested
color:
white to off-white
biological source: human
recombinant: expressed in E. coli
Assay: ≥98% (SDS-PAGE)
form: lyophilized
potency: ≤0.1 ng/mL
mol wt: 14.6 kDa
packaging: pkg of 20 μg
technique(s): cell culture | mammalian: suitable
impurities: __
color: __
biological source:
human
recombinant:
expressed in E. coli
Assay:
≥98% (SDS-PAGE)
form:
lyophilized
potency:
≤0.1 ng/mL
mol wt:
14.6 kDa
packaging:
pkg of 20 μg
technique(s):
cell culture | mammalian: suitable
impurities:
__
color:
__
biological source: human
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
potency: ≤0.5 ng/mL
mol wt: 7.5 kDa
packaging: pkg of 50 μg
technique(s): cell culture | mammalian: suitable
impurities: <0.1 EU/μg endotoxin, tested
color: white to off-white
biological source:
human
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
potency:
≤0.5 ng/mL
mol wt:
7.5 kDa
packaging:
pkg of 50 μg
technique(s):
cell culture | mammalian: suitable
impurities:
<0.1 EU/μg endotoxin, tested
color:
white to off-white
biological source: human
recombinant: expressed in E. coli
Assay: ≥98% (HPLC)≥98% (SDS-PAGE)
form: lyophilized
potency: 5.0-10.0 ng/mL ED50
mol wt: 16.7 kDa
packaging: pkg of 100 μg
technique(s): cell culture | mammalian: suitable
impurities: <0.1 EU/μg endotoxin, tested
color: white to off-white
biological source:
human
recombinant:
expressed in E. coli
Assay:
≥98% (HPLC)≥98% (SDS-PAGE)
form:
lyophilized
potency:
5.0-10.0 ng/mL ED50
mol wt:
16.7 kDa
packaging:
pkg of 100 μg
technique(s):
cell culture | mammalian: suitable
impurities:
<0.1 EU/μg endotoxin, tested
color:
white to off-white