T0667
Trimethoprim lactate salt
≥98%
Manufacturer: Sigma Aldrich
CAS Number: 23256-42-0
Synonym(S): 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate, 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine lactate salt
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 250 MG | T0667-250-MG | In Stock | ₹ 24,597.60 |
T0667 - 250 MG
In Stock
Quantity
1
Base Price: ₹ 24,597.60
GST (18%): ₹ 4,427.568
Total Price: ₹ 29,025.168
Quality Level
200
Assay
≥98%
form
powder
storage condition
(Keep container tightly closed in a dry and well-ventilated place.)
color
white
solubility
H2O: soluble 20 mg/mL
antibiotic activity spectrum
Gram-negative bacteriaGram-positive bacteriamycobacteria
Mode of action
DNA synthesis | interferesenzyme | inhibits
storage temp.
2-8°C
SMILES string
CC(O)C(O)=O.COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Chem-Impex International, Inc. Trimethoprim lactate salt | 23256-42-0 | MFCD00171722 | 5G | Chem-Impex International, Inc. | ₹ 33,881.76 | |
 | Sigma Aldrich Fine Chemicals Biosciences Trimethoprim lactate salt >=98% | 23256-42-0 | MFCD00171722 | 250MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 39,408.94 | |
 | Trimethoprim lactate salt | Sigma Aldrich | ₹ 24,597.60 | |
 | Propanoic acid, 2-hydroxy-, compd. with 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine (1:1) | Aaron Chemicals LLC | ₹ 941.16 - ₹ 15,486.36 |
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Description
- General description: Chemical structure: pyrimidine
- Application: Trimethoprim is primarily used as an antibacterial agent. It has dihydrofolate reductase inhibitor activity with selectivity for the prokaryote enzyme. It is used clinically to treat urinary tract infections, mild acute prostatitis, recurrent cystitis, asymptomatic bacteriuria during pregnancy and respiratory tract infections[1]. Trimethoprim lactate salt is used as a selection agent[2].
- Biochem/physiol Actions: The combination of trimethoprim and sulfamethoxazole interferes with the cellular metabolism of folic acid in the bacterial cell by blocking the biosynthesis of nucleotides. Trimethoprim binds to prokaryote-specific dihydrofolate reductase (DHFR) and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF). THF is an essential precursor in the thymidine synthesis pathway and interference with this pathway inhibits bacterial DNA synthesis[1].
- Other Notes: Keep container tightly closed in a dry and well-ventilated place.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral - Repr. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Quality Level: 200
Assay: ≥98%
form: powder
storage condition: (Keep container tightly closed in a dry and well-ventilated place.)
color: white
solubility: H2O: soluble 20 mg/mL
antibiotic activity spectrum: Gram-negative bacteriaGram-positive bacteriamycobacteria
Mode of action: DNA synthesis | interferesenzyme | inhibits
storage temp.: 2-8°C
SMILES string: CC(O)C(O)=O.COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC
Quality Level:
200
Assay:
≥98%
form:
powder
storage condition:
(Keep container tightly closed in a dry and well-ventilated place.)
color:
white
solubility:
H2O: soluble 20 mg/mL
antibiotic activity spectrum:
Gram-negative bacteriaGram-positive bacteriamycobacteria
Mode of action:
DNA synthesis | interferesenzyme | inhibits
storage temp.:
2-8°C
SMILES string:
CC(O)C(O)=O.COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC
Quality Level: 100
Assay: ≥98%
form: __
storage condition: __
color: __
solubility: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: __
SMILES string: O.[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](O)[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Quality Level:
100
Assay:
≥98%
form:
__
storage condition:
__
color:
__
solubility:
__
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
__
SMILES string:
O.[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](O)[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Quality Level: 200
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__
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__
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__
color:
__
solubility:
__
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__
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−20°C
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Quality Level: 200
Assay: ≥99% (titration)
form: crystalline powder
storage condition: __
color: __
solubility: water: 0.333 g/mL, clear to slightly hazy, colorless
antibiotic activity spectrum: __
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SMILES string: [Na+].OCC(CO)(CO)NCCS([O-])(=O)=O
Quality Level:
200
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≥99% (titration)
form:
crystalline powder
storage condition:
__
color:
__
solubility:
water: 0.333 g/mL, clear to slightly hazy, colorless
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
__
SMILES string:
[Na+].OCC(CO)(CO)NCCS([O-])(=O)=O