Description

• General description: Vancomycin is a nonribosomal glycopeptide antibiotic characterized by its branched, tricyclic, and glycosylated structure. Unlike beta-lactam antibiotics, vancomycin operates by inhibiting bacterial cell wall synthesis at an earlier stage. Its spectrum of activity is primarily directed against aerobic and anaerobic gram-positive bacteria, encompassing a wide range of isolates, including those that exhibit resistance to β-lactams. Vancomycin is notably effective against Gram-positive organisms such as Clostridium difficile, Listeria monocytogenes, Streptococcus pyogenes, Streptococcus pneumoniae, Streptococcus agalactiae, Streptococcus viridans, Streptococcus bovis, Staphylococcus epidermidis, Actinomyces species, and Lactobacillus species. It demonstrates exceptional efficacy in combating methicillin-resistant Staphylococcus aureus (MRSA). Furthermore, vancomycin is a valuable tool for preventing the proliferation of bacterial contaminants in studies related to cell biology and biochemistry.
• Application: Vancomycin hydrochloride from Streptomyces orientalis has been used: in the research the effects of antibiotic-induced depletion of Firmicutes and Bacteroidetes on dysregulation of energy homeostasis in obesity[1]in the research of non-O157 Shiga toxin-producing Escherichia coli Isolates from Bovine Farms[2] to research the antimicrobial susceptibility of Bifidobacterium strains in various organisms[3]
• Biochem/physiol Actions: Mode of action: Inhibits incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. Antimicrobial Spectrum: Active against Gram-positive bacteria
• Features and Benefits: Effective against a wide range of Gram-positive bacteria, including MRSACommonly used in Cell Biology and Biochemical applications
• Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
• Other Notes: For additional information on our range of Biochemicals, please complete this form.