PyClock
6-Chloro-benzotriazole-1-yloxy-tris-pyrrolidinophosphonium hexafluorophosphate Novabiochem®
Manufacturer: Sigma Aldrich
CAS Number: 893413-42-8
Synonym(S): PyClock, 6-Chloro-benzotriazole-1-yloxy-tris-pyrrolidinophosphonium hexafluorophosphate
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 G | 8.51087-25-G | In Stock | ₹ 12,110.00 |
| 100 G | 8.51087-100-G | In Stock | ₹ 35,429.99 |
8.51087 - 25 G
In Stock
Quantity
1
Base Price: ₹ 12,110.00
GST (18%): ₹ 2,179.80
Total Price: ₹ 14,289.80
Quality Level
200
product line
Novabiochem®
Assay
≥98.0% (HPLC)
form
powder
reaction suitability
reaction type: Coupling Reactions
manufacturer/tradename
Novabiochem®
mp
165-175 °C
application(s)
peptide synthesis
storage temp.
2-8°C
InChI
1S/C18H27ClN6OP.F6P/c19-16-7-8-17-18(15-16)25(21-20-17)26-27(22-9-1-2-10-22,23-11-3-4-12-23)24-13-5-6-14-24;1-7(2,3,4,5)6/h7-8,15H,1-6,9-14H2;/q+1;-1
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | eMolecules 6-Chlorobenzotriazole-1-yloxy-tris-pyrrolidinophosphonium hexafluorophosphate | 893413-42-8 | MFCD14560589 | 25g | eMolecules | ₹ 11,111.68 | |
 | eMolecules Ambeed / ((6-Chloro-1H-benzo[d][123]triazol-1-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate / 5g / 534579522 / A285552 / / 893413-42-8 / MFCD14560589 / 554.840 / C18H27ClF6N6OP2 | eMolecules | ₹ 2,416.21 | |
 | 893413-42-8 | Pyclock | A2B Chem | ₹ 1,197.84 - ₹ 5,048.04 |
Related Products
Description
- General description: PyClocK is the 6-chloro analog of PyBOP. Reaction of protected amino acids with PyClocK in the presence of base generates the corresponding 6-chloro-1-benzotriazolyl (Cl-OBt) ester. These active esters are considerably more reactive than those produced when using PyBOP or HBTU, owing to 6-chloro-1-hydroxybenzotriazole (Cl-HOBt) being more acidic than HOBt. PyClocK is an excellent coupling reagent for situations where carboxyl activation may be sluggish, such as cyclizations and fragment condensations, as unlike imminium-based reagents such as HBTU and HATU excess PyClocK cannot cause end-capping of peptide chains. Associated Protocols and Technical ArticlesGuide to Selection of Coupling Reagents
- Analysis Note: Color (visual): white to slight yellow to beigeAppearance of substance (visual): powderIdentity (IR): conformsAssay (HPLC, area%): ≥ 98.0 % (a/a)Solubility (5% in NMP (1-Methyl-2-pyrrolidone)): clear
- Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
Quality Level: 200
product line: Novabiochem®
Assay: ≥98.0% (HPLC)
form: powder
reaction suitability: reaction type: Coupling Reactions
manufacturer/tradename: Novabiochem®
mp: 165-175 °C
application(s): peptide synthesis
storage temp.: 2-8°C
InChI: 1S/C18H27ClN6OP.F6P/c19-16-7-8-17-18(15-16)25(21-20-17)26-27(22-9-1-2-10-22,23-11-3-4-12-23)24-13-5-6-14-24;1-7(2,3,4,5)6/h7-8,15H,1-6,9-14H2;/q+1;-1
Quality Level: 200
product line: Novabiochem®
Assay: ≥99.0% (HPLC)
form: powder
reaction suitability: reaction type: Coupling Reactions
manufacturer/tradename: Novabiochem®
mp: 142-148 °C
application(s): peptide synthesis
storage temp.: 2-8°C
InChI: __
Quality Level: 200
product line: Novabiochem®
Assay: __
form: solid
reaction suitability: reaction type: Coupling Reactions
manufacturer/tradename: Novabiochem®
mp: 104-109 °C
application(s): peptide synthesis
storage temp.: 2-8°C
InChI: 1S/C5H12FN2/c1-7(2)5(6)8(3)4/h1-4H3/q+1
