8.51095

PyOxim

≥99.0% (HPLC), for peptide synthesis, Novabiochem®

Manufacturer: Sigma Aldrich

CAS Number: 153433-21-7

Synonym(S): PyOxim, 1-Cyano-2-ethoxy-2-oxoethylideneaminooxy-tris-pyrrolidino-phosphonium hexafluorophosphate

Select a Size

Pack Size SKU Availability Price
25 G 8.51095-25-G In Stock ₹ 11,880.01
100 G 8.51095-100-G In Stock ₹ 40,266.96

8.51095 - 25 G

₹ 11,880.01

In Stock

Quantity

1

Base Price: ₹ 11,880.01

GST (18%): ₹ 2,138.402

Total Price: ₹ 14,018.412

product name

PyOxim, Novabiochem®

Quality Level

300

product line

Novabiochem®

Assay

≥99.0% (HPLC)

form

powder

reaction suitability

reaction type: Coupling Reactions

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

storage temp.

15-25°C

InChI

1S/C17H29N5O3P.F6P/c1-2-24-17(23)16(15-18)19-25-26(20-9-3-4-10-20,21-11-5-6-12-21)22-13-7-8-14-22;1-7(2,3,4,5)6/h2-14H2,1H3;/q+1;-1/b19-16+;

Other Options

Image Product Name Manufacturer Price Range
728462
PyOxim
Sigma Aldrich ₹ 7,036.25 - ₹ 33,330.18

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Description

  • General description: PyOxim [1] is a novel reagent which mediates coupling reactions with efficiencies superior to HATU and PyBOP and comparable to COMU. It is has excellent solubility in DMF and is stable in solution under an inert atmosphere for two days. Unlike HATU and HBTU, it cannot cause chain terminating side reactions and is, therefore, ideal for the synthesis of cyclic peptides. Furthermore, it is not explosive under normal operating conditions and is less likely to exhibit allergenicity compared to other coupling reagents.Associated Protocols and Technical ArticlesGuide to Selection of Coupling ReagentsLiterature references[1] R. Subiros-Funosas, et al. (2010) Org. Biomol. Chem., 8, 3665.
  • Features and Benefits: Mediates coupling with superior efficiency to PyBOP, TBTU, and HCTUMediates coupling with low racemization or epimerizationIdeal for fragment condensation and synthesis of cyclic peptides as the reagent cannot cause guanidinylationExcellent solubility in DMF and NMP
  • Analysis Note: Colour (visual): white to off whiteAppearance of substance (visual): powderIdentity (IR): passes testAssay (HPLC, area%): ≥ 99.0 %Solubility (1 mmole in 2 ml DMF): clearly soluble
  • Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFETY INFORMATION

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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