Fmoc-Ser(tBu)-Wang resin LL (100-200 mesh)

Description

• General description: Pre-loaded resin for synthesis of peptide acids containing a C-terminal serine amino-acid residue by Fmoc SPPS. Prepared from a low load Wang resin, to help facilitate the synthesis of longer peptides. Associated Protocols and Technical Articles Cleavage and Deprotection Protocols for Fmoc SPPS
• Application: Applications of Fmoc-Ser(tBu)-Wang resin LL (100-200 mesh) include: In the preparation of a peptide thioester intermediate for use in the solid-phase synthesis of peptide and glycopeptide thioesters using a side-chain-anchoring strategy.[1]As a solid support in the synthesis of a peptide substrate for use in a reaction to prepare disubstituted pyrazino-oxazine derivatives.[2]In the synthesis of a peptide intermediate for use in the solid-phase synthesis of tetramic acid derivatives, which have potential applications as pharmaceuticals.[3]
• Linkage: Replaces: 04-12-2086
• Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany