Description

• General description: Tannic acid is the simplest hydrolyzable tannin. The chemical structure of tannic acid has a glucose molecule in its core connected to 10 galloyls groups via aliphatic ester bonds. TA is one of the most abundant natural polyphenols, which can be colorless to yellow in color, and of astringent taste. It can be sourced from the bark of oak, chestnut, hemlock, mangrove, etc.
• Application: Tannic acid has been used: as a reference standard to measure the total hydrolyzable tannins in Oak root bark tannin-methanol extract using a UV/Vis spectrophotometer as a blood-brain barrier (BBB) impermeable, transcytosis-inhibiting drug in spheroid culture medium as a flushing agent to test its effects on metal ions, total organic carbon, and organic matter of soil as an inhibitor of free ovalbumin (OVA) uptake by the endocytic mechanism on dendritic cells
• Biochem/physiol Actions: Tannic acid has many pharmacological properties such as antioxidant, anti-inflammatory, antimicrobial, and anti-tumor effects. It also exerts anti-aging, wound healing, and neuroprotective activities. TA is traditionally used as a tanning agent in the food, leather, adhesive, and pharmaceutical industries. It is a natural crosslinker that is useful in building polymeric networks and can be used to design biomedical hydrogels.