Description

• General description: β-Eudesmol is an aromatic, oxygenated sesquiterpene compound.[1] It is primarily observed in the bark of mangolia trees and can also be extracted from other medical herbs such as Cryptomeria japonica, Atractylodes lancea, Pterocarpus santalinus, Ginkgo biloba, and Nardostachys jatamansi.[2]
• Application: β-Eudesmol has been used:as a treatment to test its antioxidant, anti-inflammatory, cell preservation effects on human dermal fibroblasts (HDFs)[2]as a reference standard to investigate if metabolically engineered E. coli extracted terpene synthase (Tps) genes encode for β-eudesmol synthase by using gas chromatography-mass spectrometry (GC/MS) analysis[3]to test its antiviral effects against herpes simplex virus type 1 (HSV-1)[4]to test its reversal effects of cocaine-induced planarian behavior[1]
• Biochem/physiol Actions: β-Eudesmol has many pharmacological benefits.[2] It is an active ingredient present in many essential oils, showing antioxidant and antimicrobial activities.[5] β-Eudesmol elicits its antifungal and anti-wood-decay fungal activities in leaf essential oil of Litsea coreana [6] tree, and the twigs of Taiwania cryptomerioides trees[7] respectively. It suppresses tumor cell proliferation, growth, and migration of human tumor cells.[8][9] β-Eudesmol is known to have various protective effects on the nervous system.[1]