Guanidine thiocyanate
BioReagent, for molecular biology, ≥99%
Manufacturer: Sigma Aldrich
CAS Number: 593-84-0
Synonym(S): Guanidinium rhodanide, Guanidinium thiocyanate
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 G | 50981-100-G | In Stock | ₹ 8,811.55 |
| 500 G | 50981-500-G | In Stock | ₹ 24,237.18 |
50981 - 100 G
In Stock
Quantity
1
Base Price: ₹ 8,811.55
GST (18%): ₹ 1,586.079
Total Price: ₹ 10,397.629
biological source
synthetic
Quality Level
200
grade
for molecular biology
product line
BioReagent
Assay
≥99%
form
powder
technique(s)
RNA extraction: suitable
impurities
DNases, none detected RNases, none detected phosphatases, none detected proteases, none detected
color
colorless to white,
mp
115-122 °C120-122 °C (lit.)
Other Options
Related Products
Description
- Application: Guanidine thiocyanate has been used as a component of the stabilization buffer for RNA lysis.[1] It can be used for deactivation of endogenous RNases leading to denaturation of nucleoprotein complexes.[2] It is also suitable for denaturation of macromolecules such as nucleic acids and proteins and for RNA isolation.
- Biochem/physiol Actions: Guanidine thiocyanate (GTC) plays a role in protein denaturation.[3] It is involved in separation of ribosomal ribonucleic acid (rRNA) from ribosomes and denatures ribonuclease (RNase).[4] GTC has been studied in the unfolding and refolding of fluorescent proteins (FP).[5] It can be used along with phenol and chloroform for extraction of RNA.[6]
- Principle: Guanidine thiocyanate interferes with the hydrogen bonds and intramolecular interactions of macromolecules. It solubilizes the proteins resulting in disintegration of cellular structures.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1C
Supplementary Hazards
EUH032
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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biological source: synthetic
Quality Level: 200
grade: for molecular biology
product line: BioReagent
Assay: ≥99%
form: powder
technique(s): RNA extraction: suitable
impurities: DNases, none detected RNases, none detected phosphatases, none detected proteases, none detected
color: colorless to white,
mp: 115-122 °C120-122 °C (lit.)
biological source: __
Quality Level: __
grade: __
product line: __
Assay: __
form: __
technique(s): __
impurities: __
color: __
mp: __
biological source: __
Quality Level: __
grade: __
product line: __
Assay: __
form: __
technique(s): __
impurities: __
color: __
mp: __
