Guanidine thiocyanate solution
Manufacturer: Sigma Aldrich
CAS Number: 593-84-0
Synonym(S): Guanidine isothiocyanate, Guanidinium isothiocyanate, Guanidinium rhodanide, Guanidinium thiocyanate
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 ML | 50983-50-ML | In Stock | ₹ 7,837.30 |
| 250 ML | 50983-250-ML | In Stock | ₹ 29,422.35 |
50983 - 50 ML
In Stock
Quantity
1
Base Price: ₹ 7,837.30
GST (18%): ₹ 1,410.714
Total Price: ₹ 9,248.014
grade
for molecular biology
Quality Level
200
product line
BioUltra
concentration
~6 M in H2O
impurities
DNases, none detected RNases, none detected insoluble matter, passes filter test phosphatases, none detected proteases, none detected
refractive index
n20/D 1.474-1.483
pH
4.5-7.0 (25 °C)
anion traces
chloride (Cl-): ≤500 mg/kgsulfate (SO42-): ≤50 mg/kg
cation traces
Al: ≤1 mg/kgAs: ≤0.1 mg/kgBa: ≤1 mg/kgBi: ≤1 mg/kgCa: ≤5 mg/kgCd: ≤1 mg/kgCo: ≤1 mg/kgCr: ≤1 mg/kgCu: ≤1 mg/kgFe: ≤1 mg/kgK: ≤20 mg/kgLi: ≤1 mg/kgMg: ≤1 mg/kgMn: ≤1 mg/kgMo: ≤1 mg/kgNa: ≤500 mg/kgNi: ≤1 mg/kgPb: ≤1 mg/kgSr: ≤1 mg/kgZn: ≤1 mg/kg
absorption
cut-off at 280 nm
Other Options
Related Products
Description
- General description: Guanidine thiocyanate is a chaotropic agent that functions as a strong protein denaturant. It is widely used in RNA isolation protocols. Guanidine thiocyanate can irreversibly inactivate RNase and DNase and breaks cellular membranes. It dissolves proteins by disturbing their secondary structures. Guanidine thiocyanate also separates nucleoproteins from nucleic acids and aids the digestion of the proteins with proteases. It improves the activity of proteinase K thus making it the protease of choice.
- Application: Guanidine thiocyanate solution has been used to extract: plasma RNA from human immunodeficiency virus (HIV)-infected and control patientstotal RNA from collected tissues (shoots, flowers, fruits, and seeds)in reverse transcription-polymerase chain reaction (RT-PCR) analysis, RNA from teratocarcinoma cell line (Tera-1)
- Caution: possibly crystallized product can be dissolved again by slightly heating to 40-50 °C.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1C
Supplementary Hazards
EUH032
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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grade: for molecular biology
Quality Level: 200
product line: BioUltra
concentration: ~6 M in H2O
impurities: DNases, none detected RNases, none detected insoluble matter, passes filter test phosphatases, none detected proteases, none detected
refractive index: n20/D 1.474-1.483
pH: 4.5-7.0 (25 °C)
anion traces: chloride (Cl-): ≤500 mg/kgsulfate (SO42-): ≤50 mg/kg
cation traces: Al: ≤1 mg/kgAs: ≤0.1 mg/kgBa: ≤1 mg/kgBi: ≤1 mg/kgCa: ≤5 mg/kgCd: ≤1 mg/kgCo: ≤1 mg/kgCr: ≤1 mg/kgCu: ≤1 mg/kgFe: ≤1 mg/kgK: ≤20 mg/kgLi: ≤1 mg/kgMg: ≤1 mg/kgMn: ≤1 mg/kgMo: ≤1 mg/kgNa: ≤500 mg/kgNi: ≤1 mg/kgPb: ≤1 mg/kgSr: ≤1 mg/kgZn: ≤1 mg/kg
absorption: cut-off at 280 nm
grade: __
Quality Level: __
product line: __
concentration: __
impurities: __
refractive index: __
pH: __
anion traces: __
cation traces: __
absorption: __
grade: __
Quality Level: __
product line: __
concentration: __
impurities: __
refractive index: __
pH: __
anion traces: __
cation traces: __
absorption: __
