646563

DL-Dithiothreitol solution

1 M in H2O

Manufacturer: Supelco

CAS Number: 3483-12-3

Synonym(S): (±)-threo-1,4-Dimercapto-2,3-butanediol solution, DTT

Select a Size

Pack Size SKU Availability Price
10 X 0.5 ML 646563-10-X-0.5-ML In Stock ₹ 10,998.20

646563 - 10 X 0.5 ML

₹ 10,998.20

In Stock

Quantity

1

Base Price: ₹ 10,998.20

GST (18%): ₹ 1,979.676

Total Price: ₹ 12,977.876

form

liquid

Quality Level

100

reaction suitability

reagent type: reductant

concentration

1 M in H2O

density

1.04 g/mL at 20 °C1.035 g/mL at 25 °C

SMILES string

O[C@H](CS)[C@H](O)CS

InChI

1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1

InChI key

VHJLVAABSRFDPM-QWWZWVQMSA-N

Other Options

Image Product Name Manufacturer Price Range
56-000-01SET
MilliporeSigma™ Calbiochem™ SPUTOLYSIN™ Reagent
MilliporeSigma™ ₹ 50,764.46
50-184-5435
Sigma Aldrich Fine Chemicals Biosciences DL-Dithiothreitol BioUltra, for molecular biology, >=99.5% (RT) | 3483-12-3 | MFCD00004877 | 25G
Sigma Aldrich Fine Chemicals Biosciences ₹ 1,65,464.48
50-184-5434
Sigma Aldrich Fine Chemicals Biosciences DL-Dithiothreitol BioUltra, for molecular biology | 3483-12-3 | MFCD00004877 | 1g
Sigma Aldrich Fine Chemicals Biosciences ₹ 14,463.92
50-184-5437
Sigma Aldrich Fine Chemicals Biosciences DL-Dithiothreitol solution | 3483-12-3 | MFCD00004877 | 250 mL
Sigma Aldrich Fine Chemicals Biosciences ₹ 53,389.44
6814339
MilliporeSigma™ Calbiochem™ Cleland’s Reagent
Fischer Scientific --
23-315-51GM
MilliporeSigma™ Calbiochem™ Cleland’s Reagent
Fischer Scientific ₹ 7,614.84
23-315-55GM
MilliporeSigma™ Calbiochem™ Cleland’s Reagent
Fischer Scientific ₹ 13,972.80
23-315-510GM
MilliporeSigma™ Calbiochem™ Cleland’s Reagent
Fischer Scientific ₹ 26,140.29
23-315-525GM
MilliporeSigma™ Calbiochem™ Cleland’s Reagent
Fischer Scientific ₹ 63,158.68
23-315-5100GM
MilliporeSigma™ Calbiochem™ Cleland’s Reagent
Fischer Scientific ₹ 1,50,823.46

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Description

  • General description: Dithiothreitol (DTT) is used in proteomics applications to maintain sulfhydryl (-SH) groups in the reduced state and for quantitative reduction of disulfide (-S-S-) groups. It is a frequently used reagent in buffers due to its ability to reduce the oxidation state of a protein sample and preserves enzymatic activity. DTT is oxidized to the cyclic disulfide during the reduction of other disulfides in the solution.
  • Application: DL-Dithiothreitol solution has been used: in western blot analysisas a supplement in lysis buffer to study its effects on sperm lysisas a component of cold homogenization buffer, and chilled wash buffer for the isolation of nuclei from frozen rat tissuesin sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), chromatography, modification of cysteine-containing compounds
  • Features and Benefits: Low toxicity and reduced odor compared to other thiol compounds.

SAFETY INFORMATION

Pictograms

GHS05

Signal Word

Danger

Hazard Statements

H315,H318

Precautionary Statements

P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P362 + P364

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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1 M in H2O...


form:
liquid

Quality Level:
100

reaction suitability:
reagent type: reductant

concentration:
1 M in H2O

density:
1.04 g/mL at 20 °C1.035 g/mL at 25 °C

SMILES string:
O[C@H](CS)[C@H](O)CS

InChI:
1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1

InChI key:
VHJLVAABSRFDPM-QWWZWVQMSA-N

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OB(O)C1CCC1

InChI:
1S/C4H9BO2/c6-5(7)4-2-1-3-4/h4,6-7H,1-3H2

InChI key:
MIUALDDWOKMYDA-UHFFFAOYSA-N

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Sigma Aldrich

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Nc1cc(n[nH]1)-c2ccc(Br)cc2

InChI:
1S/C9H8BrN3/c10-7-3-1-6(2-4-7)8-5-9(11)13-12-8/h1-5H,(H3,11,12,13)

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FTCWIBNIYIEHDT-UHFFFAOYSA-N

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COCC(OC)OC

InChI:
1S/C5H12O3/c1-6-4-5(7-2)8-3/h5H,4H2,1-3H3

InChI key:
DYOZNCVZPFIXLU-UHFFFAOYSA-N