Description

• General description: 14:0 Cardiolipin or TMCL (1,1′,2,2′-tetramyristoyl cardiolipin) is a saturated CL and exists as gel at low temperatures.[1]
• Application: 14:0 Cardiolipin (ammonium salt) has been used as stable isotope-labeled standard prior to yeast strains high performance liquid chromatography electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS).[5] It may be used as an internal standard in mass spectroscopy[6] and in liposome preparation for electrophysiological studies.[7]
• Biochem/physiol Actions: Cardiolipin participates in proton uptake pathway and also maintains the structure of enzymes involved.[9] Cardiolipin maintains the mitochondrial function, membrane potential and structural support for the inner mitochondrial membrane and proteins in it. Concentration and composition changes of cardiolipin have been implicated in pathological conditions including ischemia, hypothyroidism, aging, heart failure and cardioskeletal myopathy.) Cardiolipin can form micelles/vesicles naturally.[3]
• Packaging: 5 mL Amber Glass Screw Cap Vial (710332P-200mg)