A2024

Apramycin sulfate salt

Manufacturer: Sigma Aldrich

CAS Number: 65710-07-8

Synonym(S): Nebramycin II

Select a Size

Pack Size SKU Availability Price
1 G A2024-1-G In Stock ₹ 10,673.45
5 G A2024-5-G In Stock ₹ 40,442.20

A2024 - 1 G

₹ 10,673.45

In Stock

Quantity

1

Base Price: ₹ 10,673.45

GST (18%): ₹ 1,921.221

Total Price: ₹ 12,594.671

biological source

Streptomyces tenebrarius

Quality Level

200

form

powder

color

white to brown

antibiotic activity spectrum

Gram-negative bacteria

Mode of action

protein synthesis | interferes

storage temp.

2-8°C

SMILES string

OS(O)(=O)=O.CN[C@H]1[C@@H](O)[C@H]2O[C@H](O[C@@H]3[C@@H](N)C[C@@H](N)[C@H](O)[C@H]3O)[C@H](N)C[C@@H]2O[C@@H]1O[C@H]4O[C@H](CO)[C@@H](N)[C@H](O)[C@H]4O

InChI

1S/C21H41N5O11.H2O4S/c1-26-11-14(30)18-8(33-20(11)37-21-16(32)13(29)10(25)9(4-27)34-21)3-7(24)19(36-18)35-17-6(23)2-5(22)12(28)15(17)31;1-5(2,3)4/h5-21,26-32H,2-4,22-25H2,1H3;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11+,12+,13+,14-,15-,16-,17-,18+,19+,20-,21-;/m1./s1

InChI key

WGLYHYWDYPSNPF-RQFIXDHTSA-N

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Description

  • General description: Chemical structure: aminoglycoside
  • Application: Apramycin is used to study antibiotic resistance [1][2] as well as protein synthesis translocation-step inhibition in bacteria and prokaryotes.
  • Biochem/physiol Actions: Apramycin inhibits protein synthesis by blocking translocation. It is also able to bind to the eukaryotic decoding site.[3] At low concentrations it inhibits elongation and induces misreading of mRNA during protein synthesis.[4]
  • Packaging: 1G, 5G
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.Storage class (TRGS 510): Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects.

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H360FD

Precautionary Statements

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Show Difference

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Sigma Aldrich

A2024

--


biological source:
Streptomyces tenebrarius

Quality Level:
200

form:
powder

color:
white to brown

antibiotic activity spectrum:
Gram-negative bacteria

Mode of action:
protein synthesis | interferes

storage temp.:
2-8°C

SMILES string:
OS(O)(=O)=O.CN[C@H]1[C@@H](O)[C@H]2O[C@H](O[C@@H]3[C@@H](N)C[C@@H](N)[C@H](O)[C@H]3O)[C@H](N)C[C@@H]2O[C@@H]1O[C@H]4O[C@H](CO)[C@@H](N)[C@H](O)[C@H]4O

InChI:
1S/C21H41N5O11.H2O4S/c1-26-11-14(30)18-8(33-20(11)37-21-16(32)13(29)10(25)9(4-27)34-21)3-7(24)19(36-18)35-17-6(23)2-5(22)12(28)15(17)31;1-5(2,3)4/h5-21,26-32H,2-4,22-25H2,1H3;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11+,12+,13+,14-,15-,16-,17-,18+,19+,20-,21-;/m1./s1

InChI key:
WGLYHYWDYPSNPF-RQFIXDHTSA-N

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__

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Sigma Aldrich

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liquid

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SMILES string:
CC(=O)CCCO

InChI:
1S/C5H10O2/c1-5(7)3-2-4-6/h6H,2-4H2,1H3

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JSHPTIGHEWEXRW-UHFFFAOYSA-N

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SMILES string:
Cl.NCc1ccc(cc1)S(N)(=O)=O

InChI:
1S/C7H10N2O2S.ClH/c8-5-6-1-3-7(4-2-6)12(9,10)11;/h1-4H,5,8H2,(H2,9,10,11);1H

InChI key:
SIACJRVYIPXFKS-UHFFFAOYSA-N