DMT-2′O-Methyl-rA(bz) Phosphoramidite
configured for (ÄKTA® and OligoPilot®), configured for ABI
Manufacturer: Sigma Aldrich
CAS Number: 110782-31-5
Synonym(S): DMT-2′-O-Me-rA(bz) amidite, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-adenosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 2 G | A211150-2-G | In Stock | ₹ 19,203.55 |
| 5 G | A211150-5-G | In Stock | ₹ 48,853.23 |
| 10 G | A211150-10-G | In Stock | ₹ 97,630.68 |
A211150 - 2 G
In Stock
Quantity
1
Base Price: ₹ 19,203.55
GST (18%): ₹ 3,456.639
Total Price: ₹ 22,660.189
biological source
non-animal source (no BSE/TSE risk)
Quality Level
300
product line
Proligo Reagents
Assay
≥99% (31P-NMR)≥99.0% (reversed phase HPLC)
form
powder
technique(s)
oligo synthesis: suitable
impurities
≤0.1% single unspecified Impurity (reversed phase HPLC)≤0.3% mA2 (reversed phase HPLC, Hydrolysate)≤0.3% mA3 (reversed phase HPLC, DMT-rA(bz)me)≤0.3% water content (Karl Fischer)≤0.5% P(III) Impurities 100-169ppm (31P-NMR)≤1.0% mA1 (reversed phase HPLC, DMT-rA(bz)me-DMT)≤3% residual Solvent content
color
white to off-white
λ
conforms (UV/VIS Identity)
suitability
conforms to structure for H-NMRconforms to structure for LC-MS
Other Options
Related Products
Description
- General description: DMT-2′O-Methyl-rA(bz) Phosphoramidite is a 2′O-Methyl RNA monomer that is compatible with fast deprotection schemes that are based on the application of aliphatic amines, such as methylamine. Modern phosphoramidite-mediated synthesis has enabled routine high-yielding preparations of 2′O-Methyl RNA oligonucleotides. High-quality RNA phosphoramidites are key to low failure rates, the high biological activity of synthesis products, and cost-effectiveness. 2′O-Methyl RNA is a nucleic acid analog that is characterized by the exceptional hybridization properties that it imparts with complementary DNA or RNA, as well as increased stability against enzymatic degradation compared to natural nucleic acids.
- Application: 2′O-Methyl RNA nucleoside including DMT-2′O-Methyl-rA(bz) Phosphoramidite can be advantageously incorporated in nucleic acid probes with RNA or DNA for in-vivo or in-vitro applications to convey nuclease resistance.The unique combination of properties of 2′O-Methyl RNA had found widespread use in the fields of: Diagnostic probes Aptamer and ribozyme development Mixed 2′O-Methyl-RNA/DNA antisense molecules (a)
- Legal Information: OligoPilot is a registered trademark of Cytiva
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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biological source: non-animal source (no BSE/TSE risk)
Quality Level: 300
product line: Proligo Reagents
Assay: ≥99% (31P-NMR)≥99.0% (reversed phase HPLC)
form: powder
technique(s): oligo synthesis: suitable
impurities: ≤0.1% single unspecified Impurity (reversed phase HPLC)≤0.3% mA2 (reversed phase HPLC, Hydrolysate)≤0.3% mA3 (reversed phase HPLC, DMT-rA(bz)me)≤0.3% water content (Karl Fischer)≤0.5% P(III) Impurities 100-169ppm (31P-NMR)≤1.0% mA1 (reversed phase HPLC, DMT-rA(bz)me-DMT)≤3% residual Solvent content
color: white to off-white
λ: conforms (UV/VIS Identity)
suitability: conforms to structure for H-NMRconforms to structure for LC-MS
biological source: non-animal source (no BSE/TSE risk)
Quality Level: 300
product line: Proligo Reagents
Assay: ≥99% (31P-NMR)≥99.0% (reversed phase HPLC)
form: powder
technique(s): oligo synthesis: suitable
impurities: ≤0.3% water content (Karl Fischer)≤0.5% P(III) Impurities 100-169ppm (31P-NMR)≤0.5% single Impurity (reversed phase HPLC)≤3% residual Solvent content
color: white to off-white
λ: conforms (UV/VIS Identity)
suitability: conforms to structure for H-NMRconforms to structure for LC-MS
biological source: non-animal source (no BSE/TSE risk)
Quality Level: 300
product line: Proligo Reagents
Assay: ≥99% (31P-NMR)≥99.0% (reversed phase HPLC)
form: powder
technique(s): oligo synthesis: suitable
impurities: ≤0.3% water content (Karl Fischer)≤0.5% P(III) Impurities 100-169ppm (31P-NMR)≤0.5% single Impurity (reversed phase HPLC)≤3% residual Solvent content
color: white to off-white
λ: conforms (UV/VIS Identity)
suitability: conforms to structure for H-NMRconforms to structure for LC-MS
