DMT-2′O-Methyl-rC(ac) Phosphoramidite
configured for ABI
Manufacturer: Sigma Aldrich
CAS Number: 199593-09-4
Synonym(S): N-acetyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-cytidine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 G | C213150-5-G | In Stock | ₹ 48,744.98 |
| 10 G | C213150-10-G | In Stock | ₹ 1,02,729.25 |
C213150 - 5 G
In Stock
Quantity
1
Base Price: ₹ 48,744.98
GST (18%): ₹ 8,774.096
Total Price: ₹ 57,519.076
biological source
non-animal source (no BSE/TSE risk)
Quality Level
300
product line
Proligo Reagents
Assay
≥99% (31P-NMR)≥99.0% (reversed phase HPLC)
form
powder
impurities
≤0.3% mC2 (reversed phase HPLC, Hydrolysate)≤0.3% mC3 (reversed phase HPLC, DMT-rC(ac)me)≤0.3% mC4 (reversed phase HPLC, DMT-rC(ac)me-Ac)≤0.3% water content (Karl Fischer)≤0.5% P(III) Impurities 100-169ppm (31P-NMR)≤0.5% single Impurity (redox titration)≤1.0% mC1 (redox titration, DMT-rC(ac)me-DMT)≤3% residual Solvent content
color
white to off-white
suitability
conforms to structure for H-NMRconforms to structure for LC-MS
compatibility
configured for ABI
storage temp.
2-8°C
Other Options
Related Products
Description
- General description: DMT-2′O-Methyl-rC(ac) Phosphoramidite is a 2′O-Methyl RNA monomer that is compatible with fast deprotection schemes that are based on the application of aliphatic amines, such as methylamine. Modern phosphoramidite mediated synthesis has enabled routine high-yielding preparations of 2′O-Methyl RNA oligonucleotides. High-quality RNA phosphoramidites are key to low failure rates, the high biological activity of synthesis products, and cost-effectiveness. 2′O-Methyl RNA is a nucleic acid analog that is characterized by the exceptional hybridization properties that it imparts with complimentary DNA or RNA, as well as increased stability against enzymatic degradation compared to natural nucleic acids.
- Application: 2′O-Methyl RNA nucleoside including DMT-2′O-Methyl-rC(ac) Phosphoramidite can be advantageously incorporated in nucleic acid probes with RNA or DNA for in-vivo or in-vitro applications to convey nuclease resistance.The unique combination of properties of 2′O-Methyl RNA had found widespread use in the fields of: Diagnostic probesAptamer and ribozyme development Mixed 2′O-Methyl-RNA/DNA antisense molecules
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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biological source: non-animal source (no BSE/TSE risk)
Quality Level: 300
product line: Proligo Reagents
Assay: ≥99% (31P-NMR)≥99.0% (reversed phase HPLC)
form: powder
impurities: ≤0.3% mC2 (reversed phase HPLC, Hydrolysate)≤0.3% mC3 (reversed phase HPLC, DMT-rC(ac)me)≤0.3% mC4 (reversed phase HPLC, DMT-rC(ac)me-Ac)≤0.3% water content (Karl Fischer)≤0.5% P(III) Impurities 100-169ppm (31P-NMR)≤0.5% single Impurity (redox titration)≤1.0% mC1 (redox titration, DMT-rC(ac)me-DMT)≤3% residual Solvent content
color: white to off-white
suitability: conforms to structure for H-NMRconforms to structure for LC-MS
compatibility: configured for ABI
storage temp.: 2-8°C
biological source: non-animal source (no BSE/TSE risk)
Quality Level: 300
product line: Proligo Reagents
Assay: ≥99% (31P-NMR)≥99.0% (reversed phase HPLC)
form: powder
impurities: ≤0.3% water content (Karl Fischer)≤0.5% P(III) Impurities 100-169ppm (31P-NMR)≤0.5% single Impurity (reversed phase HPLC)≤3% residual Solvent content
color: white to off-white
suitability: conforms to structure for H-NMRconforms to structure for LC-MS
compatibility: __
storage temp.: __
biological source: Clostridium histolyticum
Quality Level: 200
product line: __
Assay: __
form: powder
impurities: __
color: __
suitability: suitable for release of rat epididymal adipocytes and hepatocytes (for methodology see Type II and Type IV)
compatibility: __
storage temp.: −20°C
