A2487
Cotrimoxazole, Ready Made Solution
100 mg/mL in DMSO
Manufacturer: Sigma Aldrich
CAS Number: 8064-90-2
Synonym(S): Trimethoprim-Sulfamethoxazole, TMP-SMX
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 ML | A2487-1-ML | In Stock | ₹ 40,517.98 |
A2487 - 1 ML
In Stock
Quantity
1
Base Price: ₹ 40,517.98
GST (18%): ₹ 7,293.236
Total Price: ₹ 47,811.216
form
liquid
Quality Level
200
concentration
100 mg/mL in DMSO
color
colorless to faint yellow
antibiotic activity spectrum
Gram-negative bacteriaGram-positive bacteriafungiparasites
Mode of action
DNA synthesis | interferes
shipped in
dry ice
storage temp.
−20°C
InChI
1S/C14H18N4O3.C10H11N3O3S/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15;1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h5-7H,4H2,1-3H3,(H4,15,16,17,18);2-6H,11H2,1H3,(H,12,13)
InChI key
WZRJTRPJURQBRM-UHFFFAOYSA-N
Related Products
Description
- Application: Cotrimoxazole has been used as an antimicrobial agent.[1][2]
- Biochem/physiol Actions: Cotrimoxazole, a combination of trimethoprim and sulfamethoxazole, interferes with the cellular metabolism of folic acid in the bacterial cell by blocking the biosynthesis of nucleotides. Trimethoprim binds to dihydrofolate reductase (DHFR) which inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF), resulting in an antimicrobial effect. Sulfamethoxazole interferes with the synthesis of nucleic acids in sensitive microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid. The net effect of these actions is to inhibit thymidine synthesis which prevents bacterial DNA synthesis.
- Packaging: 1ml
- Preparation Note: prepared using a 1:5 mixture of trimethoprim:sulfamethoxazole
- Other Notes: Keep container tightly closed in a dry and well-ventilated place.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 3 - Repr. 2
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
form: liquid
Quality Level: 200
concentration: 100 mg/mL in DMSO
color: colorless to faint yellow
antibiotic activity spectrum: Gram-negative bacteriaGram-positive bacteriafungiparasites
Mode of action: DNA synthesis | interferes
shipped in: dry ice
storage temp.: −20°C
InChI: 1S/C14H18N4O3.C10H11N3O3S/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15;1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h5-7H,4H2,1-3H3,(H4,15,16,17,18);2-6H,11H2,1H3,(H,12,13)
InChI key: WZRJTRPJURQBRM-UHFFFAOYSA-N
form:
liquid
Quality Level:
200
concentration:
100 mg/mL in DMSO
color:
colorless to faint yellow
antibiotic activity spectrum:
Gram-negative bacteriaGram-positive bacteriafungiparasites
Mode of action:
DNA synthesis | interferes
shipped in:
dry ice
storage temp.:
−20°C
InChI:
1S/C14H18N4O3.C10H11N3O3S/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15;1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h5-7H,4H2,1-3H3,(H4,15,16,17,18);2-6H,11H2,1H3,(H,12,13)
InChI key:
WZRJTRPJURQBRM-UHFFFAOYSA-N
form: powder
Quality Level: 300
concentration: __
color: white
antibiotic activity spectrum: __
Mode of action: __
shipped in: __
storage temp.: __
InChI: 1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChI key: __
form:
powder
Quality Level:
300
concentration:
__
color:
white
antibiotic activity spectrum:
__
Mode of action:
__
shipped in:
__
storage temp.:
__
InChI:
1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChI key:
__
form: lyophilized powder
Quality Level: 300
concentration: __
color: __
antibiotic activity spectrum: __
Mode of action: __
shipped in: __
storage temp.: __
InChI: __
InChI key: __
form:
lyophilized powder
Quality Level:
300
concentration:
__
color:
__
antibiotic activity spectrum:
__
Mode of action:
__
shipped in:
__
storage temp.:
__
InChI:
__
InChI key:
__
form: powder
Quality Level: 200
concentration: __
color: __
antibiotic activity spectrum: __
Mode of action: __
shipped in: __
storage temp.: __
InChI: 1S/2C5H5N5.H2O4S/c2*6-4-3-5(9-1-7-3)10-2-8-4;1-5(2,3)4/h2*1-2H,(H3,6,7,8,9,10);(H2,1,2,3,4)
InChI key: LQXHSCOPYJCOMD-UHFFFAOYSA-N
form:
powder
Quality Level:
200
concentration:
__
color:
__
antibiotic activity spectrum:
__
Mode of action:
__
shipped in:
__
storage temp.:
__
InChI:
1S/2C5H5N5.H2O4S/c2*6-4-3-5(9-1-7-3)10-2-8-4;1-5(2,3)4/h2*1-2H,(H3,6,7,8,9,10);(H2,1,2,3,4)
InChI key:
LQXHSCOPYJCOMD-UHFFFAOYSA-N