A9528
Amphotericin B solubilized
powder, suitable for cell culture, BioXtra
Manufacturer: Sigma Aldrich
CAS Number: 1397-89-3
Synonym(S): Amphotericin B from Streptomyces sp., Fungizone
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | A9528-50-MG | In Stock | ₹ 5,823.85 |
| 100 MG | A9528-100-MG | In Stock | ₹ 11,117.28 |
| 500 MG | A9528-500-MG | In Stock | ₹ 52,328.05 |
| 1 G | A9528-1-G | In Stock | ₹ 1,00,066.30 |
| 5 G | A9528-5-G | In Stock | ₹ 3,74,501.70 |
A9528 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 5,823.85
GST (18%): ₹ 1,048.293
Total Price: ₹ 6,872.143
Quality Level
300
sterility
γ-irradiated
product line
BioXtra
form
powder
technique(s)
cell culture | mammalian: suitable
antibiotic activity spectrum
fungiyeast
Mode of action
cell membrane | interferes
storage temp.
2-8°C
SMILES string
C[C@H]1O[C@@H](O[C@@H]2C[C@@H]3O[C@](O)(C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\2)C[C@H](O)[C@H]3C(O)=O)[C@@H](O)[C@@H](N)[C@@H]1O
InChI
1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Amphotericin B | Supelco | ₹ 38,266.38 | |
 | Amphotericin B | Sigma Aldrich | ₹ 38,721.03 | |
| | Amphotericin B for microbiological assay | Sigma Aldrich | ₹ 16,107.60 | |
| | Amphotericin B for peak identification | Sigma Aldrich | ₹ 16,107.60 | |
 | Amphotericin B | Sigma Aldrich | ₹ 3,604.73 - ₹ 12,362.15 | |
| | Amphotericin B from Streptomyces sp. | Sigma Aldrich | ₹ 11,344.60 - ₹ 17,66,791.55 | |
| | Amphotericin B from Streptomyces sp. | Sigma Aldrich | ₹ 21,238.65 - ₹ 2,23,081.60 |
Related Products
Description
- General description: Chemical structure: polyene
- Application: Amphotericin B is a polyene antifungal antibiotic from Streptomyce sp. It has a high affinity for sterols, especially ergosterols, of both fungal and bacterial cell membranes. Normal usage in maintenance of antifungal cell cultures is 2.5 mg/L with penicillin and streptomycin used in the medium.
- Biochem/physiol Actions: Amphotericin B binds to sterols, forming pores in the membrane, and causing small molecules to leak out. The product is most effective against fungi and yeast.
- Packaging: Solubilized Amphotericin B is packaged in amber glass bottle, with the contents inside an inserted fused cone.
- Components: This product is a colloidal suspension of Amphotericin B, using deoxycholate as the solubilizing agent. The formulation is ~45% Amphotericin B and 35% sodium deoxycholate in sodium phosphate and sodium chloride.
- Caution: Amphotericin B remains active for 3 days in culture at 37°C. At -20°C, and with protection from air and light, the product remains active for 5 years.
- Preparation Note: Amphotericin B is soluble at 19.6-20.4 mg/ml in water, at natural pH without heating, giving a yellowish clear to slightly hazy solution. Aqueous solutions cannot be sterile filtered due to poor solubility. If reconstituted in sterile water, there is no need to filter sterilize.It is also soluble in DMSO (30-40 mg/mL) and in dimethylformamide (2-4 mg/mL).
- Other Notes: Keep container tightly closed in a dry and well-ventilated place. Product is sensitive to light and moisture. Keep in a dry place.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
STOT RE 1
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
Quality Level: 300
sterility: γ-irradiated
product line: BioXtra
form: powder
technique(s): cell culture | mammalian: suitable
antibiotic activity spectrum: fungiyeast
Mode of action: cell membrane | interferes
storage temp.: 2-8°C
SMILES string: C[C@H]1O[C@@H](O[C@@H]2C[C@@H]3O[C@](O)(C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\2)C[C@H](O)[C@H]3C(O)=O)[C@@H](O)[C@@H](N)[C@@H]1O
InChI: 1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
Quality Level:
300
sterility:
γ-irradiated
product line:
BioXtra
form:
powder
technique(s):
cell culture | mammalian: suitable
antibiotic activity spectrum:
fungiyeast
Mode of action:
cell membrane | interferes
storage temp.:
2-8°C
SMILES string:
C[C@H]1O[C@@H](O[C@@H]2C[C@@H]3O[C@](O)(C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\2)C[C@H](O)[C@H]3C(O)=O)[C@@H](O)[C@@H](N)[C@@H]1O
InChI:
1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
Quality Level: 100
sterility: __
product line: __
form: powder
technique(s): __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: __
SMILES string: OC(=O)CCCCCCCC(O)=O
InChI: 1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)
Quality Level:
100
sterility:
__
product line:
__
form:
powder
technique(s):
__
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
__
SMILES string:
OC(=O)CCCCCCCC(O)=O
InChI:
1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)
Quality Level: 100
sterility: __
product line: __
form: (Liquid or Viscous Liquid or Semi-Solid to Solid)
technique(s): __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: __
SMILES string: COC(=O)CCCCCCCC(O)=O
InChI: 1S/C10H18O4/c1-14-10(13)8-6-4-2-3-5-7-9(11)12/h2-8H2,1H3,(H,11,12)
Quality Level:
100
sterility:
__
product line:
__
form:
(Liquid or Viscous Liquid or Semi-Solid to Solid)
technique(s):
__
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
__
SMILES string:
COC(=O)CCCCCCCC(O)=O
InChI:
1S/C10H18O4/c1-14-10(13)8-6-4-2-3-5-7-9(11)12/h2-8H2,1H3,(H,11,12)
Quality Level: 200
sterility: __
product line: __
form: powder
technique(s): __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: −20°C
SMILES string: C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(O)=O
InChI: 1S/C9H17N3O4/c1-4(10)7(13)11-5(2)8(14)12-6(3)9(15)16/h4-6H,10H2,1-3H3,(H,11,13)(H,12,14)(H,15,16)/t4-,5-,6-/m0/s1
Quality Level:
200
sterility:
__
product line:
__
form:
powder
technique(s):
__
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
−20°C
SMILES string:
C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(O)=O
InChI:
1S/C9H17N3O4/c1-4(10)7(13)11-5(2)8(14)12-6(3)9(15)16/h4-6H,10H2,1-3H3,(H,11,13)(H,12,14)(H,15,16)/t4-,5-,6-/m0/s1