A9789

Anisomycin

from Streptomyces griseolus, ≥98% (HPLC), solid, protein synthesis inhibitor

Manufacturer: Sigma Aldrich

CAS Number: 22862-76-6

Synonym(S): (2R,3S,4S)-2-(4-Methoxybenzyl)-3,4-pyrrolidinediol-3-acetate, 2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate, Flagecidin

Select a Size

Pack Size SKU Availability Price
5 MG A9789-5-MG In Stock ₹ 6,765.63
25 MG A9789-25-MG In Stock ₹ 21,985.58
100 MG A9789-100-MG In Stock ₹ 66,541.28

A9789 - 5 MG

₹ 6,765.63

In Stock

Quantity

1

Base Price: ₹ 6,765.63

GST (18%): ₹ 1,217.813

Total Price: ₹ 7,983.443

product name

Anisomycin from Streptomyces griseolus, ≥98% (HPLC), solid

Quality Level

300

Assay

≥98% (HPLC)

form

solid

color

white to faint yellow

solubility

H2O: 2 mg/mL (Aqueous solutions are stable over a wide range of pH at room temperature.)DMSO: 20 mg/mLmethanol: 20 mg/mL

antibiotic activity spectrum

neoplastics

Mode of action

protein synthesis | interferes

storage temp.

2-8°C

SMILES string

COc1ccc(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)cc1

Other Options

Image Product Name Manufacturer Price Range
A5862
Anisomycin, Ready Made Solution from Streptomyces griseolus
Sigma Aldrich ₹ 6,992.95
A5862
Anisomycin, Ready Made Solution from Streptomyces griseolus
Sigma Aldrich ₹ 6,992.95
A9789
Anisomycin
Sigma Aldrich ₹ 6,765.63 - ₹ 66,541.28
AI66035
22862-76-6 | 3,4-Pyrrolidinediol, 2-[(4-methoxyphenyl)methyl]-, 3-acetate,(2R,3S,4S)-
A2B Chem ₹ 1,283.40 - ₹ 60,063.12

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Description

  • Biochem/physiol Actions: Antibiotic isolated from Streptomyces griseolus that inhibits protein synthesis. Acts by inhibiting peptidyl transferase activity in eukaryote ribosomes. Reported to induce apoptosis in a variety of cells including promyelocytic leukemia cells, Jurkat cells, ventricular myocytes, and colon adenocarcinoma cells. Initiates intracellular signals and immediate early gene induction. Selective signaling agonist. Potent Jun-NH2 terminal kinase (JNK) agonist. Activates mitogen-activated protein (MAP) kinases (JNK/SAPK and p38/RK). Antiprotozoal agent.
  • Caution: Hygroscopic

SAFETY INFORMATION

Pictograms

GHS06

Signal Word

Danger

Hazard Statements

H301

Precautionary Statements

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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product name:
Anisomycin from Streptomyces griseolus, ≥98% (HPLC), solid

Quality Level:
300

Assay:
≥98% (HPLC)

form:
solid

color:
white to faint yellow

solubility:
H2O: 2 mg/mL (Aqueous solutions are stable over a wide range of pH at room temperature.)DMSO: 20 mg/mLmethanol: 20 mg/mL

antibiotic activity spectrum:
neoplastics

Mode of action:
protein synthesis | interferes

storage temp.:
2-8°C

SMILES string:
COc1ccc(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)cc1

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SMILES string:
Cl.Nc1c(Br)cc(Br)cc1CN[C@@H]2CC[C@@H](O)CC2