B5936

Brefeldin A

from Penicillium brefeldianum, Ready Made Solution, 10 mg/mL in DMSO

Manufacturer: Sigma Aldrich

CAS Number: 20350-15-6

Synonym(S): Synergisidin, γ,4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid λ-lactone, Ascotoxin, BFA, Cyanein, Decumbin

Select a Size

Pack Size SKU Availability Price
200 μL B5936-200-μL In Stock ₹ 15,162.60

B5936 - 200 μL

₹ 15,162.60

In Stock

Quantity

1

Base Price: ₹ 15,162.60

GST (18%): ₹ 2,729.268

Total Price: ₹ 17,891.868

biological source

Penicillium brefeldianum

Quality Level

200

vapor pressure

0.56 hPa ( 20 °C)

form

solution

autoignition temp.

301 °C

concentration

10 mg/mL in DMSO

solubility

DMSO: 10 mg/mL

antibiotic activity spectrum

neoplastics

Mode of action

cell membrane | interferes

shipped in

wet ice

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Description

  • Application: Brefeldin A produced from Penicillium brefeldianum may be used to study protein and lipid transport between Golgi complex and the cell surface.
  • Biochem/physiol Actions: Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus by inhibiting transport of proteins from ER to Golgi and inducing retrograde protein transport from the Golgi apparatus to the endoplasmic reticulum.[1] BFA inhibits the transport of sphingomyelin to the surface of mammalian cells.[2] The ester derivatives of BFA exhibit anti-cancer properties.[3]
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.Store under inert gas. Hygroscopic.Storage class (TRGS 510): Combustible liquids

SAFETY INFORMATION

WGK

WGK 2

Flash Point(F)

188.6 °F

Flash Point(C)

87 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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200

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0.56 hPa ( 20 °C)

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301 °C

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10 mg/mL in DMSO

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DMSO: 10 mg/mL

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neoplastics

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cell membrane | interferes

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wet ice

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