B6542
Brefeldin A
≥99% (HPLC and TLC), BioXtra, for molecular biology
Manufacturer: Sigma Aldrich
CAS Number: 20350-15-6
Synonym(S): γ,4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid λ-lactone, Ascotoxin, BFA, Cyanein, Decumbin
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | B6542-5-MG | In Stock | ₹ 24,540.28 |
| 25 MG | B6542-25-MG | In Stock | ₹ 75,655.93 |
B6542 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 24,540.28
GST (18%): ₹ 4,417.25
Total Price: ₹ 28,957.53
biological source
Penicillium brefeldianum
Quality Level
300
grade
for molecular biology
product line
BioXtra
Assay
≥99% (HPLC and TLC)
form
powder
mol wt
280.36
solubility
DMSO: 10 mg/mL (Store stock solutions at -20 °C)
antibiotic activity spectrum
neoplastics
Mode of action
protein synthesis | interferes
Other Options
Related Products
Description
- General description: Brefeldin induces ADP-ribosylation of CtBP1/BARS protein that regulates the intracellular trafficking and movement of secretory proteins from endoplasmic reticulum to Golgi apparatus.[1][2]
- Application: Suitable for molecular biology studies of secretory proteins and mechanisms of intracellular transport
- Biochem/physiol Actions: Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus. BFA is an activator of the sphingomyelin cycle. Brefeldin A-mediated apoptosis has been observed in human tumor cells.
- Principle: Brefeldin is a fungal metabolite that disrupts protein secretion in eukaryotic cells by disrupting the Golgi apparatus. It does not affect the process of protein synthesis.[1][2]
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
biological source: Penicillium brefeldianum
Quality Level: 300
grade: for molecular biology
product line: BioXtra
Assay: ≥99% (HPLC and TLC)
form: powder
mol wt: 280.36
solubility: DMSO: 10 mg/mL (Store stock solutions at -20 °C)
antibiotic activity spectrum: neoplastics
Mode of action: protein synthesis | interferes
biological source:
Penicillium brefeldianum
Quality Level:
300
grade:
for molecular biology
product line:
BioXtra
Assay:
≥99% (HPLC and TLC)
form:
powder
mol wt:
280.36
solubility:
DMSO: 10 mg/mL (Store stock solutions at -20 °C)
antibiotic activity spectrum:
neoplastics
Mode of action:
protein synthesis | interferes
biological source: __
Quality Level: 200
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Assay: 97%
form: liquid
mol wt: __
solubility: __
antibiotic activity spectrum: __
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200
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__
product line:
__
Assay:
97%
form:
liquid
mol wt:
__
solubility:
__
antibiotic activity spectrum:
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biological source: __
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biological source:
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__
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__
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mol wt:
__
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antibiotic activity spectrum:
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biological source: __
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form: liquid
mol wt: __
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