G3767

Trisialoganglioside-GT1b from bovine brain

lyophilized powder, ≥96% (TLC)

Manufacturer: Sigma Aldrich

CAS Number: 59247-13-1

Synonym(S): Ganglioside GT1b

Select a Size

Pack Size SKU Availability Price
1 MG G3767-1-MG In Stock ₹ 29,985.25
5 MG G3767-5-MG In Stock ₹ 88,104.68

G3767 - 1 MG

₹ 29,985.25

In Stock

Quantity

1

Base Price: ₹ 29,985.25

GST (18%): ₹ 5,397.345

Total Price: ₹ 35,382.595

Quality Level

200

Assay

≥96% (TLC)

form

lyophilized powder

solubility

DMSO: solubleethanol: soluble

storage temp.

−20°C

InChI

1S/C88H157N5O44/c1-4-6-8-10-12-14-16-18-19-21-23-25-27-29-31-33-56(107)92-37-51(45(101)32-30-28-26-24-22-20-17-15-13-11-9-7-5-2)124-80-66(113)65(112)70(54(42-98)127-80)129-82-69(116)77(136-87(84(120)121)35-46(102)57(89)72(132-87)61(108)49(105)38-94)71(55(43-99)128-82)130-79-60(93-44(3)100)75(63(110)52(40-96)125-79)131-81-68(115)76(64(111)53(41-97)126-81)135-86(83(118)119)34-47(103)59(91)74(134-86)67(114)78(117)137-88(85(122)123)36-48(104)58(90)73(133-88)62(109)50(106)39-95/h30,32,45-55,57-82,94-99,101-106,108-117H,4-29,31,33-43,89-91H2,1-3H3,(H,92,107)(H,93,100)(H,118,119)(H,120,121)(H,122,123)/b32-30+/t45?,46-,47-,48-,49?,50?,51?,52-,53-,54+,55-,57+,58+,59+,60-,61?,62?,63+,64+,65+,66+,67?,68-,69-,70+,71+,72+,73+,74+,75-,76+,77-,78?,79+,80+,81+,82+,86+,87+,88+/m0/s1

InChI key

NVNPEYQWKCQBBU-ADMXJUBYSA-N

Other Options

Image Product Name Manufacturer Price Range
50-210-0492
Enzo Life Sciences Ganglioside GT1b . trisodium salt (bovine brain) (5 mg) CAS: 59247-13-1
Enzo Life Sciences ₹ 43,700.63
860059P
Ganglioside GT1b
Sigma Aldrich ₹ 30,310.00 - ₹ 98,117.80
AW54021
59247-13-1 | Ganglioside GT1b
A2B Chem ₹ 10,010.52 - ₹ 30,544.92

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Description

  • Amino Acid Sequence: Cer-Glc-Gal(NeuAc-NeuAc)-GalNAc-Gal-NeuAc
  • General description: Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum. They contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage. For classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.
  • Application: Trisialoganglioside-GT1b from bovine brain has been used:in high performance thin layer chromatography (HPTLC)[1]in membrane GM1 assays[2]as reference standards for TLC (thin layer chromatography) and as antigens for ELISA (enzyme-linked immunosorbent assay)[3]
  • Biochem/physiol Actions: Ganglioside marker for metastatic brain tumors. Modulates cellular differentiation; prevents glutamate neurotoxicity; inhibits mitogenesis stimulated by lectins such as Con A. Converted to GD1b by bacterial and mammalian sialidases.
  • Analysis Note: Homogeneous aqueous preparations can be obtained by suspending the compound in water, buffer or cell culture medium and sonicating briefly to facilitate the micelle formation.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Quality Level:
200

Assay:
≥96% (TLC)

form:
lyophilized powder

solubility:
DMSO: solubleethanol: soluble

storage temp.:
−20°C

InChI:
1S/C88H157N5O44/c1-4-6-8-10-12-14-16-18-19-21-23-25-27-29-31-33-56(107)92-37-51(45(101)32-30-28-26-24-22-20-17-15-13-11-9-7-5-2)124-80-66(113)65(112)70(54(42-98)127-80)129-82-69(116)77(136-87(84(120)121)35-46(102)57(89)72(132-87)61(108)49(105)38-94)71(55(43-99)128-82)130-79-60(93-44(3)100)75(63(110)52(40-96)125-79)131-81-68(115)76(64(111)53(41-97)126-81)135-86(83(118)119)34-47(103)59(91)74(134-86)67(114)78(117)137-88(85(122)123)36-48(104)58(90)73(133-88)62(109)50(106)39-95/h30,32,45-55,57-82,94-99,101-106,108-117H,4-29,31,33-43,89-91H2,1-3H3,(H,92,107)(H,93,100)(H,118,119)(H,120,121)(H,122,123)/b32-30+/t45?,46-,47-,48-,49?,50?,51?,52-,53-,54+,55-,57+,58+,59+,60-,61?,62?,63+,64+,65+,66+,67?,68-,69-,70+,71+,72+,73+,74+,75-,76+,77-,78?,79+,80+,81+,82+,86+,87+,88+/m0/s1

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NVNPEYQWKCQBBU-ADMXJUBYSA-N

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1S/C5H6O3/c6-4-2-1-3-5(7)8-4/h1-3H2

InChI key:
VANNPISTIUFMLH-UHFFFAOYSA-N