Disialoganglioside GD1a from bovine brain
≥95% (TLC), lyophilized powder
Manufacturer: Sigma Aldrich
CAS Number: 12707-58-3
Synonym(S): Ganglioside GD1a, disialo from bovine brain
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | G2392-1-MG | In Stock | ₹ 16,345.75 |
| 5 MG | G2392-5-MG | In Stock | ₹ 51,039.88 |
G2392 - 1 MG
In Stock
Quantity
1
Base Price: ₹ 16,345.75
GST (18%): ₹ 2,942.235
Total Price: ₹ 19,287.985
Quality Level
200
Assay
≥95% (TLC)
form
lyophilized powder
solubility
DMSO: soluble
storage temp.
−20°C
InChI
1S/C86H152N4O39.2Na/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-51(100)50(90-60(105)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2)46-118-80-69(111)67(109)72(57(43-94)120-80)123-82-71(113)78(129-86(84(116)117)39-53(102)62(88-48(4)98)77(128-86)65(107)55(104)41-92)74(59(45-96)122-82)124-79-63(89-49(5)99)75(66(108)56(42-93)119-79)125-81-70(112)68(110)73(58(44-95)121-81)126-85(83(114)115)38-52(101)61(87-47(3)97)76(127-85)64(106)54(103)40-91;;/h34,36,50-59,61-82,91-96,100-104,106-113H,6-33,35,37-46H2,1-5H3,(H,87,97)(H,88,98)(H,89,99)(H,90,105)(H,114,115)(H,116,117);;/q;2*+1/p-2/b36-34+;;/t50-,51+,52?,53?,54-,55-,56?,57?,58?,59?,61+,62+,63?,64-,65-,66?,67?,68?,69?,70?,71?,72?,73?,74?,75?,76?,77?,78?,79?,80?,81?,82?,85?,86?;;/m0../s1
InChI key
CWLDKTAXQZEVQN-CUEXFKMESA-L
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Enzo Life Sciences Ganglioside GD1a. disodium salt (bovine brain) (1mg). CAS: 12707-58-3 | Enzo Life Sciences | ₹ 8,265.10 | |
 | Ganglioside GD1a | Sigma Aldrich | ₹ 34,228.65 - ₹ 1,10,674.80 | |
 | 12707-58-3 | GangliosideGD1adisodiumsalt | A2B Chem | ₹ 20,192.16 |
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Description
- Amino Acid Sequence: Cer-Glc-Gal(NeuAc)-GalNAc-Gal-NeuAc
- General description: Gangliosides are in the neuronal cell membranes and endoplasmic reticulum. They consist of a sialylated polysaccharide chain linked via β-glycosidic linkage to ceramide.[1] They are also located in body fluids and plasma.[2] GD1a consists of a neutral tetrasaccharide core with one sialic acid on the internal galactose and another sialic acid on the non-reducing terminal galactose.[3]
- Application: Disialoganglioside GD1a from bovine brain has been used:as a receptor for the detection of murine norovirus-1 (MNV-1) by RT-PCR[4]as a glycolipid to study the interaction between protein human endogenous retrovirus W family pHERV-W ENV and glycolipids by enzyme-linked immunosorbent assay (ELISA)[5]as a reference standard to analyze the ganglioside signatures of prostate cancer cells by high-performance liquid chromatography[6]
- Biochem/physiol Actions: Gangliosides are involved in cellular functions such as the differentiation of neurons, formation of axons, synapses,[7] cell proliferation, differentiation, adhesion, and cell death.[2] In addition, gangliosides form microdomains on the outer surface of the cell membranes that are involved in signal transduction and help in the formation of dendrites.[7] Gangliosides act as Ca2+ binding co-factors during synaptic transmission.[2]
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Quality Level: 200
Assay: ≥95% (TLC)
form: lyophilized powder
solubility: DMSO: soluble
storage temp.: −20°C
InChI: 1S/C86H152N4O39.2Na/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-51(100)50(90-60(105)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2)46-118-80-69(111)67(109)72(57(43-94)120-80)123-82-71(113)78(129-86(84(116)117)39-53(102)62(88-48(4)98)77(128-86)65(107)55(104)41-92)74(59(45-96)122-82)124-79-63(89-49(5)99)75(66(108)56(42-93)119-79)125-81-70(112)68(110)73(58(44-95)121-81)126-85(83(114)115)38-52(101)61(87-47(3)97)76(127-85)64(106)54(103)40-91;;/h34,36,50-59,61-82,91-96,100-104,106-113H,6-33,35,37-46H2,1-5H3,(H,87,97)(H,88,98)(H,89,99)(H,90,105)(H,114,115)(H,116,117);;/q;2*+1/p-2/b36-34+;;/t50-,51+,52?,53?,54-,55-,56?,57?,58?,59?,61+,62+,63?,64-,65-,66?,67?,68?,69?,70?,71?,72?,73?,74?,75?,76?,77?,78?,79?,80?,81?,82?,85?,86?;;/m0../s1
InChI key: CWLDKTAXQZEVQN-CUEXFKMESA-L
Quality Level: 200
Assay: __
form: __
solubility: __
storage temp.: __
InChI: 1S/C6H12O6.C3H8O3/c7-1-2-3(8)4(9)5(10)6(11)12-2;4-1-3(6)2-5/h2-11H,1H2;3-6H,1-2H2/t2-,3-,4-,5-,6-;/m1./s1
InChI key: BCPVZFFJGCURNR-OCOFDJSDSA-N
Quality Level: 200
Assay: __
form: liquid
solubility: __
storage temp.: room temp
InChI: __
InChI key: __
