Lipid A, diphosphoryl from Escherichia coli F583 (Rd mutant)
Manufacturer: Sigma Aldrich
Synonym(S): Diphosphoryl Lipid A from E.Coli.
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | L5399-1-MG | In Stock | ₹ 14,970.98 |
| 5 MG | L5399-5-MG | In Stock | ₹ 60,338.55 |
L5399 - 1 MG
In Stock
Quantity
1
Base Price: ₹ 14,970.98
GST (18%): ₹ 2,694.776
Total Price: ₹ 17,665.756
biological source
Escherichia coli (F583 Rd mutant)
Quality Level
200
form
lyophilized powder
shipped in
ambient
storage temp.
2-8°C
SMILES string
CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)C(OCC2OC(OP(O)(O)=O)C(NC(=O)CC(O)CCCCCCCCCCC)C(OC(=O)CC(O)CCCCCCCCCCC)C2O)OC(CO)C1OP(O)(O)=O
InChI
1S/C94H178N2O25P2/c1-7-13-19-25-31-37-38-44-50-56-62-68-84(103)115-78(66-60-54-48-42-35-29-23-17-11-5)72-86(105)119-92-88(96-82(101)71-77(65-59-53-47-41-34-28-22-16-10-4)114-83(102)67-61-55-49-43-36-30-24-18-12-6)93(116-79(73-97)90(92)120-122(107,108)109)113-74-80-89(106)91(118-85(104)70-76(99)64-58-52-46-40-33-27-21-15-9-3)87(94(117-80)121-123(110,111)112)95-81(100)69-75(98)63-57-51-45-39-32-26-20-14-8-2/h75-80,87-94,97-99,106H,7-74H2,1-6H3,(H,95,100)(H,96,101)(H2,107,108,109)(H2,110,111,112)
InChI key
GZQKNULLWNGMCW-UHFFFAOYSA-N
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Description
- General description: Lipid A is the fundamental structure of lipopolysaccharides (LPS), present in bacteria.[1]
- Application: Lipid A, diphosphoryl from Escherichia coli F583 (Rd mutant) has been used:to study the effect of various lipid A molecules on lung pericyte proliferation in vitro[2]to test on THP-1 and J774A.1 cells for neopterin and nitrite formation respectively[3]as lipopolysaccharides (LPS) derivatives in binding experiments[4]to stimulate the spleen cells and as a mitogen stimulation for toll like receptor 4 (TLR4)[5]
- Biochem/physiol Actions: Lipid A is mainly essential for the robust immunostimulatory activities of lipopolysaccharides (LPS) in human. Lipid A is the hydrophobic domain of LPS helps in anchoring LPS to the plasma membrane of bacteria. It is immunologically active and an important constituent of LPS recognised by immune system.[1]
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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biological source: Escherichia coli (F583 Rd mutant)
Quality Level: 200
form: lyophilized powder
shipped in: ambient
storage temp.: 2-8°C
SMILES string: CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)C(OCC2OC(OP(O)(O)=O)C(NC(=O)CC(O)CCCCCCCCCCC)C(OC(=O)CC(O)CCCCCCCCCCC)C2O)OC(CO)C1OP(O)(O)=O
InChI: 1S/C94H178N2O25P2/c1-7-13-19-25-31-37-38-44-50-56-62-68-84(103)115-78(66-60-54-48-42-35-29-23-17-11-5)72-86(105)119-92-88(96-82(101)71-77(65-59-53-47-41-34-28-22-16-10-4)114-83(102)67-61-55-49-43-36-30-24-18-12-6)93(116-79(73-97)90(92)120-122(107,108)109)113-74-80-89(106)91(118-85(104)70-76(99)64-58-52-46-40-33-27-21-15-9-3)87(94(117-80)121-123(110,111)112)95-81(100)69-75(98)63-57-51-45-39-32-26-20-14-8-2/h75-80,87-94,97-99,106H,7-74H2,1-6H3,(H,95,100)(H,96,101)(H2,107,108,109)(H2,110,111,112)
InChI key: GZQKNULLWNGMCW-UHFFFAOYSA-N
biological source: Escherichia coli (O55:B5)
Quality Level: 200
form: aqueous solution
shipped in: wet ice
storage temp.: 2-8°C
SMILES string: __
InChI: __
InChI key: __
biological source: Escherichia coli (O55:B5)
Quality Level: 200
form: aqueous solution
shipped in: wet ice
storage temp.: 2-8°C
SMILES string: __
InChI: __
InChI key: __
