Leupeptin
powder, ≥95% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 103476-89-7
Synonym(S): Leupeptin hemisulfate salt, Acetyl-Leu-Leu-Arg-al, N-Acetyl-L-leucyl-L-leucyl-L-argininal hemisulfate salt
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | L5793-5-MG | In Stock | ₹ 30,299.18 |
| 25 MG | L5793-25-MG | In Stock | ₹ 81,003.48 |
| 100 MG | L5793-100-MG | In Stock | ₹ 2,34,209.70 |
L5793 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 30,299.18
GST (18%): ₹ 5,453.852
Total Price: ₹ 35,753.032
product name
Leupeptin, BioUltra, microbial, ≥95% (HPLC)
biological source
microbial
Quality Level
200
product line
BioUltra
Assay
≥95% (HPLC)
form
powder
solubility
H2O: 50 mg/mL
storage temp.
−20°C
SMILES string
OS(O)(=O)=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C=O
InChI
1S/2C20H38N6O4.H2O4S/c2*1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22;1-5(2,3)4/h2*11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23);(H2,1,2,3,4)/t2*15-,16-,17-;/m00./s1
Other Options
Related Products
Description
- Biochem/physiol Actions: Inhibitor of serine and cysteine proteases. Inhibits plasmin, trypsin, papain, calpain, and cathepsin B. Does not inhibit pepsin, cathepsins A and D, thrombin, or α-chymotrypsin. Effective concentration 10-100 μM. There have been numerous studies using leupeptin to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. (Loss of cochlear hair cells is believed to be mediated by calpain.)
- Analysis Note: Leupeptin gives multiple peaks on HPLC because of the formation of tautomeric isomers in solution. Majority of contaminating peptide is racemized leupeptin.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
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product name: Leupeptin, BioUltra, microbial, ≥95% (HPLC)
biological source: microbial
Quality Level: 200
product line: BioUltra
Assay: ≥95% (HPLC)
form: powder
solubility: H2O: 50 mg/mL
storage temp.: −20°C
SMILES string: OS(O)(=O)=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C=O
InChI: 1S/2C20H38N6O4.H2O4S/c2*1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22;1-5(2,3)4/h2*11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23);(H2,1,2,3,4)/t2*15-,16-,17-;/m00./s1
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InChI: __
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