N1790
Naftifine hydrochloride
Manufacturer: Sigma Aldrich
CAS Number: 65473-14-5
Synonym(S): Naftifine HCL
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | N1790-50-MG | In Stock | ₹ 30,948.68 |
| 500 MG | N1790-500-MG | In Stock | ₹ 75,645.10 |
N1790 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 30,948.68
GST (18%): ₹ 5,570.762
Total Price: ₹ 36,519.442
Assay
≥99%
Quality Level
200
form
powder
solubility
ethanol: soluble 50 mg/mL
antibiotic activity spectrum
Gram-negative bacteriaGram-positive bacteriafungiyeast
Mode of action
cell wall synthesis | interferesenzyme | inhibits
storage temp.
2-8°C
SMILES string
Cl.CN(C\C=C\c1ccccc1)Cc2cccc3ccccc23
InChI
1S/C21H21N.ClH/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20;/h2-15H,16-17H2,1H3;1H/b11-8+;
InChI key
OLUNPKFOFGZHRT-YGCVIUNWSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | eMolecules Ambeed / (E)-N-Methyl-N-(naphthalen-1-ylmethyl)-3-phenylprop-2-en-1-amine hydrochloride / 1mg / 761204788 / A287696 / / 65473-14-5 / MFCD00059047 / 323.860 / C21H22ClN | eMolecules | ₹ 2,065.42 | |
 | Naftifine hydrochloride | Sigma Aldrich | ₹ 46,222.75 |
Related Products
Description
- Application: Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative. It is used topically to treat superficial dermatomycoses such as tinea pedis, tinea cruris, and tinea corporis[1].
- Biochem/physiol Actions: Naftifine is an allylamine compound that has antifungal and antimycotic activities. Naftifine inhibits fungal squalene epoxidase and prevents ergosterol biosynthesis. Naftifine also has antibiotic activity against Gram-positive and Gram-negative bacteria. It has demonstrated anti-inflammatory properties such as a reduction in superoxide production and a reduction in polymorphonuclear leukocyte chemotaxis/endothelial adhesion[2]. Naftifine appears to interfere with sterol biosynthesis by inhibiting the squalene 2,3-epoxidase. This inhibition results in decreased amounts of ergosterol and an accumulation of squalene in the cells[1].
- Other Notes: Keep container tightly closed in a dry and well-ventilated place.Light sensitive.
SAFETY INFORMATION
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Assay: ≥99%
Quality Level: 200
form: powder
solubility: ethanol: soluble 50 mg/mL
antibiotic activity spectrum: Gram-negative bacteriaGram-positive bacteriafungiyeast
Mode of action: cell wall synthesis | interferesenzyme | inhibits
storage temp.: 2-8°C
SMILES string: Cl.CN(C\C=C\c1ccccc1)Cc2cccc3ccccc23
InChI: 1S/C21H21N.ClH/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20;/h2-15H,16-17H2,1H3;1H/b11-8+;
InChI key: OLUNPKFOFGZHRT-YGCVIUNWSA-N
Assay:
≥99%
Quality Level:
200
form:
powder
solubility:
ethanol: soluble 50 mg/mL
antibiotic activity spectrum:
Gram-negative bacteriaGram-positive bacteriafungiyeast
Mode of action:
cell wall synthesis | interferesenzyme | inhibits
storage temp.:
2-8°C
SMILES string:
Cl.CN(C\C=C\c1ccccc1)Cc2cccc3ccccc23
InChI:
1S/C21H21N.ClH/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20;/h2-15H,16-17H2,1H3;1H/b11-8+;
InChI key:
OLUNPKFOFGZHRT-YGCVIUNWSA-N
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