O0877

Oxolinic acid

quinolone antibiotic

Manufacturer: Sigma Aldrich

CAS Number: 14698-29-4

Synonym(S): 5,8-Dihydro-5-ethyl-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid

Select a Size

Pack Size SKU Availability Price
5 G O0877-5-G In Stock ₹ 13,942.60
25 G O0877-25-G In Stock ₹ 52,869.30

O0877 - 5 G

₹ 13,942.60

In Stock

Quantity

1

Base Price: ₹ 13,942.60

GST (18%): ₹ 2,509.668

Total Price: ₹ 16,452.268

Quality Level

200

solubility

0.5 M NaOH: soluble 50 mg/mL

antibiotic activity spectrum

Gram-negative bacteria

Mode of action

DNA synthesis | interferesenzyme | inhibits

storage temp.

2-8°C

SMILES string

CCN1C=C(C(O)=O)C(=O)c2cc3OCOc3cc12

InChI

1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17)

InChI key

KYGZCKSPAKDVKC-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
11-101-3147
Oxolinic acid, ≥95% (TLC), MilliporeSigma™ Supelco™
MilliporeSigma Supelco ₹ 7,820.18
O0240000
Oxolinic acid
Sigma Aldrich ₹ 14,267.35
O0877
Oxolinic acid
Sigma Aldrich ₹ 13,942.60 - ₹ 52,869.30
CS-4499
Oxolinic acid
ChemScene ₹ 2,566.80 - ₹ 35,935.20
AB42617
14698-29-4 | Oxolinic Acid
A2B Chem ₹ 1,540.08 - ₹ 52,020.48

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Description

  • General description: Chemical structure: quinolone
  • Application: Oxolinic acid is used to study new transmissible resistance mechanisms qnrA, qnrB, qnrS, and aac(6′)Ib-cr, in Escherichia coli and Salmonella enterica. Oxolinic acid is added to culture medium for the isolation of Gardnerella vaginalis[1].
  • Biochem/physiol Actions: Oxolinic acid is a quinolone antibiotic. It is a DNA-gyrase (topoisomerase II) inhibitor used for studies on DNA winding and coiling and acts as a dopamine reuptake inhibitor for studies on dopaminergic neurotransmission processes.
  • Other Notes: 5g,25g

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Quality Level:
200

solubility:
0.5 M NaOH: soluble 50 mg/mL

antibiotic activity spectrum:
Gram-negative bacteria

Mode of action:
DNA synthesis | interferesenzyme | inhibits

storage temp.:
2-8°C

SMILES string:
CCN1C=C(C(O)=O)C(=O)c2cc3OCOc3cc12

InChI:
1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17)

InChI key:
KYGZCKSPAKDVKC-UHFFFAOYSA-N

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