T2255
Trifluorothymidine
≥99% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 70-00-8
Synonym(S): α,α,α-Trifluorothymidine, 2′-Deoxy-5-trifluoromethyluridine, Trifluorothymine deoxyriboside, Trifluridine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | T2255-100-MG | In Stock | ₹ 32,171.90 |
| 1 G | T2255-1-G | In Stock | ₹ 2,03,206.90 |
T2255 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 32,171.90
GST (18%): ₹ 5,790.942
Total Price: ₹ 37,962.842
biological source
synthetic
Quality Level
100
Assay
≥99% (HPLC)
form
powder
mp
190-193 °C (lit.)
solubility
water: 50 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(C(=O)NC2=O)C(F)(F)F
InChI
1S/C10H11F3N2O5/c11-10(12,13)4-2-15(9(19)14-8(4)18)7-1-5(17)6(3-16)20-7/h2,5-7,16-17H,1,3H2,(H,14,18,19)/t5-,6+,7+/m0/s1
InChI key
VSQQQLOSPVPRAZ-RRKCRQDMSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | eMolecules ChemScene / Trifluridine / 100mg / 536815489 / CS-1602 / 0.000 / 70-00-8 / MFCD28657276 / 296.202 / C10H11F3N2O5 | eMolecules | ₹ 5,044.62 | |
| | Sigma Aldrich Fine Chemicals Biosciences Trifluorothymidine >=99% (HPLC) | 70-00-8 | MFCD00006534 | 100MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 31,129.29 | |
 | Trifluridine | Sigma Aldrich | ₹ 52,490.43 | |
| | Trifluridine | Supelco | ₹ 32,431.70 | |
| | Trifluridine | Sigma Aldrich | ₹ 24,453.68 | |
 | Trifluorothymidine | Aaron Chemicals LLC | ₹ 1,540.08 - ₹ 35,592.96 | |
 | Trifluridine | ChemScene | ₹ 2,310.12 - ₹ 34,309.56 |
Description
- Application: Trifluorothymidine has been used as a component of selection medium to screen thymidine kinase (TK) mutants in lymphoma cells,[1] human lymphoblastoid TK6 cells,[2] and L5178Y mouse lymphoma cells.[3]
- Biochem/physiol Actions: Trifluorothymidine is a thymidine analog[4] and is light sensitive.[1] TFT serves as a thymidine kinase substrate to study enzyme specificity and kinetics.[5] Incorporation of phosphorylated TFT into DNA induces damage,[6] making it useful for DNA repair studies. TFT may also be used in the inhibition of thymidylate synthase[5] and in screening mutant thymidine kinase gene.[1]. It elicits antitumor activity in gastrointestinal (GI) cancers[7] and has therapeutic potential to treat herpetic keratitis.[4]
- Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 2 - Muta. 2 - Repr. 2
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
biological source: synthetic
Quality Level: 100
Assay: ≥99% (HPLC)
form: powder
mp: 190-193 °C (lit.)
solubility: water: 50 mg/mL, clear, colorless
storage temp.: −20°C
SMILES string: OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(C(=O)NC2=O)C(F)(F)F
InChI: 1S/C10H11F3N2O5/c11-10(12,13)4-2-15(9(19)14-8(4)18)7-1-5(17)6(3-16)20-7/h2,5-7,16-17H,1,3H2,(H,14,18,19)/t5-,6+,7+/m0/s1
InChI key: VSQQQLOSPVPRAZ-RRKCRQDMSA-N
biological source:
synthetic
Quality Level:
100
Assay:
≥99% (HPLC)
form:
powder
mp:
190-193 °C (lit.)
solubility:
water: 50 mg/mL, clear, colorless
storage temp.:
−20°C
SMILES string:
OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(C(=O)NC2=O)C(F)(F)F
InChI:
1S/C10H11F3N2O5/c11-10(12,13)4-2-15(9(19)14-8(4)18)7-1-5(17)6(3-16)20-7/h2,5-7,16-17H,1,3H2,(H,14,18,19)/t5-,6+,7+/m0/s1
InChI key:
VSQQQLOSPVPRAZ-RRKCRQDMSA-N
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Quality Level: 200
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form: solution
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solution
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biological source: Glycine max (soybean)
Quality Level: 200
Assay: ≥95% (Kunitz inhibitor, SDS-PAGE)
form: lyophilized powder
mp: __
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storage temp.: 2-8°C
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biological source:
Glycine max (soybean)
Quality Level:
200
Assay:
≥95% (Kunitz inhibitor, SDS-PAGE)
form:
lyophilized powder
mp:
__
solubility:
__
storage temp.:
2-8°C
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InChI:
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